ARG43940
anti-PIGV antibody
anti-PIGV antibody for ELISA,Flow cytometry,Western blot and Human
Overview
| Product Description | Rabbit Polyclonal antibody recognizes PIGV |
|---|---|
| Tested Reactivity | Hu |
| Tested Application | ELISA, FACS, WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | PIGV |
| Antigen Species | Human |
| Immunogen | Human PIGV recombinant protein |
| Expression System | E.coli |
| Conjugation | Un-conjugated |
| Protein Full Name | GPI mannosyltransferase 2 |
| Alternate Names | PIGV; Phosphatidylinositol Glycan Anchor Biosynthesis Class V; GPI Mannosyltransferase 2; GPI-MT-II; PIG-V; Dol-P-Man Dependent GPI Mannosyltransferase II; GPI Mannosyltransferase II; FLJ20477; Phosphatidylinositol-Glycan Biosynthesis Class V Protein; Dol-P-Man Dependent GPI Mannosyltransferase; Phosphatidylinositol Glycan, Class V; Ybr004c Homolog; EC 2.4.1.- ; HPMRS1 |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity purified with Immunogen. |
| Buffer | 0.9% NaCl, 0.2% Na2HPO4 and 4% Trehalose. |
| Stabilizer | 4% Trehalose |
| Concentration | 0.5 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | PIGV |
| Gene Full Name | Phosphatidylinositol Glycan Anchor Biosynthesis Class V |
| Background | This gene encodes a mannosyltransferase enzyme involved in the biosynthesis of glycosylphosphatidylinositol (GPI). GPI is a complex glycolipid that functions as a membrane anchor for many proteins and plays a role in multiple cellular processes including protein sorting and signal transduction. The encoded protein is localized to the endoplasmic reticulum and transfers the second mannose to the GPI backbone. Mutations in this gene are associated with hyperphosphatasia cognitive disability syndrome. Alternatively spliced transcript variants have been observed for this gene. |
| Function | Alpha-1,6-mannosyltransferase involved in glycosylphosphatidylinositol-anchor biosynthesis. Transfers the second mannose to the glycosylphosphatidylinositol during GPI precursor assembly. |
| Cellular Localization | Endoplasmic reticulum, Membrane |
| Calculated MW | 56 kDa |
