ARG64089

anti-PIK3CA / p110 alpha antibody

anti-PIK3CA / p110 alpha antibody for IHC-Formalin-fixed paraffin-embedded sections and Human

Cell Biology and Cellular Response antibody; Metabolism antibody; Neuroscience antibody

Overview

Product Description Goat Polyclonal antibody recognizes PIK3CA / p110 alpha
Tested Reactivity Hu
Predict Reactivity Ms, Rat, Cow, Dog
Tested Application IHC-P
Host Goat
Clonality Polyclonal
Isotype IgG
Target Name PIK3CA / p110 alpha
Antigen Species Mouse
Immunogen C-HQWLKDKNKGEIYD
Conjugation Un-conjugated
Alternate Names MCM; MCMTC; p110alpha; PI3-kinase subunit alpha; PI3K; CWS5; p110-alpha; PI3Kalpha; CLOVE; EC 2.7.1.153; MCAP; PtdIns-3-kinase subunit p110-alpha; EC 2.7.11.1; Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform; Phosphatidylinositol 4,5-bisphosphate 3-kinase 110 kDa catalytic subunit alpha; PI3K-alpha; PtdIns-3-kinase subunit alpha; Phosphoinositide-3-kinase catalytic alpha polypeptide; Serine/threonine protein kinase PIK3CA

Application Instructions

Application Suggestion
Tested Application Dilution
IHC-P2 - 5 µg/ml
Application Note IHC-P: Antigen Retrieval: Steam tissue section in Citrate buffer (pH 6.0).
* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.

Properties

Form Liquid
Purification Purified from goat serum by antigen affinity chromatography.
Buffer Tris saline (pH 7.3), 0.02% Sodium azide and 0.5% BSA.
Preservative 0.02% Sodium azide
Stabilizer 0.5% BSA
Concentration 0.5 mg/ml
Storage Instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database Links

GeneID: 5290 Human PIK3CA

Swiss-port # P42336 Human Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha iso

Background Phosphatidylinositol 3-kinase is composed of an 85 kDa regulatory subunit and a 110 kDa catalytic subunit. The protein encoded by this gene represents the catalytic subunit, which uses ATP to phosphorylate PtdIns, PtdIns4P and PtdIns(4,5)P2. This gene has been found to be oncogenic and has been implicated in cervical cancers. [provided by RefSeq, Jul 2008]
Research Area Cell Biology and Cellular Response antibody; Metabolism antibody; Neuroscience antibody
Calculated MW 124 kDa