ARG43246
anti-PIK3R3 / PI3K p55 gamma antibody
anti-PIK3R3 / PI3K p55 gamma antibody for ICC/IF,IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Mouse,Rat
Overview
| Product Description | Rabbit Polyclonal antibody recognizes PIK3R3 / PI3K p55 gamma |
|---|---|
| Tested Reactivity | Hu, Ms, Rat |
| Tested Application | ICC/IF, IHC-P, WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | PIK3R3 / PI3K p55 gamma |
| Antigen Species | Human |
| Immunogen | Synthetic peptide derived from Human PIK3R3 / PI3K p55 gamma. |
| Conjugation | Un-conjugated |
| Alternate Names | PtdIns-3-kinase regulatory subunit p55-gamma; PI3-kinase subunit p55-gamma; PtdIns-3-kinase regulatory subunit gamma; p55-GAMMA; p55PIK; PI3K regulatory subunit gamma; p55; PI3-kinase regulatory subunit gamma; Phosphatidylinositol 3-kinase regulatory subunit gamma; Phosphatidylinositol 3-kinase 55 kDa regulatory subunit gamma |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||||
| Positive Control | SH-SY5Y | ||||||||
| Observed Size | ~ 50 kDa |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity purified. |
| Buffer | PBS (pH 7.4), 150 mM NaCl, 0.02% Sodium azide and 50% Glycerol. |
| Preservative | 0.02% Sodium azide |
| Stabilizer | 50% Glycerol |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | PIK3R3 |
| Gene Full Name | phosphoinositide-3-kinase, regulatory subunit 3 (gamma) |
| Background | Phosphatidylinositol 3-kinase (PI3K) phosphorylates phosphatidylinositol and similar compounds, which then serve as second messengers in growth signaling pathways. PI3K is composed of a catalytic and a regulatory subunit. The protein encoded by this gene represents a regulatory subunit of PI3K. The encoded protein contains two SH2 domains through which it binds activated protein tyrosine kinases to regulate their activity. [provided by RefSeq, Jun 2016] |
| Function | Binds to activated (phosphorylated) protein-tyrosine kinases through its SH2 domain and regulates their kinase activity. During insulin stimulation, it also binds to IRS-1. [UniProt] |
| Calculated MW | 54 kDa |
