ARG44044
anti-PIK3R4 / VPS15 antibody
anti-PIK3R4 / VPS15 antibody for ICC/IF,IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Mouse,Rat
Overview
| Product Description | Rabbit Polyclonal antibody recognizes PIK3R4 / VPS15 |
|---|---|
| Tested Reactivity | Hu, Ms, Rat |
| Tested Application | ICC/IF, IHC-P, WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | PIK3R4 / VPS15 |
| Antigen Species | Human |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 1-330 of Human PIK3R4 / VPS15 (NP_055417.1). |
| Conjugation | Un-conjugated |
| Alternate Names | PIK3R4; Phosphoinositide-3-Kinase Regulatory Subunit 4; VPS15; P150; Phosphoinositide 3-Kinase Regulatory Subunit 4; Phosphoinositide 3-Kinase Adaptor Protein; PI3-Kinase Regulatory Subunit 4; PI3-Kinase P150 Subunit; EC 2.7.11.1; Phosphoinositide-3-Kinase, Regulatory Subunit 4, P150; Phosphoinositide-3-Kinase, Regulatory Subunit 4; Phosphatidylinositol 3-Kinase-Associated P150 |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity purified. |
| Buffer | PBS (pH 7.3), 0.05% proclin300 and 50% Glycerol. |
| Preservative | 0.05% proclin300 |
| Stabilizer | 50% Glycerol |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | PIK3R4 |
| Gene Full Name | Phosphoinositide-3-Kinase Regulatory Subunit 4 |
| Background | Predicted to enable protein serine/threonine kinase activity. Involved in positive regulation of phosphatidylinositol 3-kinase activity; receptor catabolic process; and regulation of cytokinesis. Located in late endosome and microtubule cytoskeleton. |
| Function | Regulatory subunit of the PI3K complex that mediates formation of phosphatidylinositol 3-phosphate; different complex forms are believed to play a role in multiple membrane trafficking pathways: PI3KC3-C1 is involved in initiation of autophagosomes and PI3KC3-C2 in maturation of autophagosomes and endocytosis. Involved in regulation of degradative endocytic trafficking and cytokinesis, probably in the context of PI3KC3-C2. |
| Cellular Localization | Cytoplasmic vesicle, Endosome, Membrane |
| Calculated MW | 153 kDa |
| PTM | Lipoprotein, Myristate, Phosphoprotein |
