ARG41044
anti-PIP4K2B antibody
anti-PIP4K2B antibody for Western blot and Human
Overview
| Product Description | Rabbit Polyclonal antibody recognizes PIP4K2B |
|---|---|
| Tested Reactivity | Hu |
| Tested Application | WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | PIP4K2B |
| Antigen Species | Human |
| Immunogen | Recombinant fusion protein corresponding to aa. 1-270 of Human PIP4K2B (NP_003550.1). |
| Conjugation | Un-conjugated |
| Alternate Names | PtdIns; PIP5KIIbeta; Diphosphoinositide kinase 2-beta; 1-phosphatidylinositol 5-phosphate 4-kinase 2-beta; Phosphatidylinositol 5-phosphate 4-kinase type II beta; PIP5P4KB; EC 2.7.1.149; PIP5K2B; 5; PIP4KII-beta; PI5P4KB; PI; PIP5KIIB; Phosphatidylinositol 5-phosphate 4-kinase type-2 beta |
Application Instructions
| Application Suggestion |
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|---|---|---|---|---|---|
| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||
| Positive Control | HepG2 | ||||
| Observed Size | 47 kDa |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity purified. |
| Buffer | PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol. |
| Preservative | 0.02% Sodium azide |
| Stabilizer | 50% Glycerol |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links |
Swiss-port # P78356 Human Phosphatidylinositol 5-phosphate 4-kinase type-2 beta |
|---|---|
| Gene Symbol | PIP4K2B |
| Gene Full Name | phosphatidylinositol-5-phosphate 4-kinase, type II, beta |
| Background | The protein encoded by this gene catalyzes the phosphorylation of phosphatidylinositol-5-phosphate on the fourth hydroxyl of the myo-inositol ring to form phosphatidylinositol-5,4-bisphosphate. This gene is a member of the phosphatidylinositol-5-phosphate 4-kinase family. The encoded protein sequence does not show similarity to other kinases, but the protein does exhibit kinase activity. Additionally, the encoded protein interacts with p55 TNF receptor. [provided by RefSeq, Jul 2008] |
| Function | Participates in the biosynthesis of phosphatidylinositol 4,5-bisphosphate. [UniProt] |
| Cellular Localization | Endoplasmic reticulum membrane; Peripheral membrane protein. Cell membrane; Peripheral membrane protein. Nucleus. Cytoplasm. Note=Associated with the plasma membrane and the endoplasmic reticulum. [UniProt] |
| Calculated MW | 47 kDa |
| PTM | Ubiquitinated by the SPOP/CUL3 complex. Ubiquitination is stimulated by PtdIns5P levels. [UniProt] |
