ARG43945
anti-PLA2G15 antibody
anti-PLA2G15 antibody for ELISA,ICC/IF,Western blot and Human
Overview
| Product Description | Rabbit Polyclonal antibody recognizes PLA2G15 |
|---|---|
| Tested Reactivity | Hu |
| Tested Application | ELISA, ICC/IF, WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | PLA2G15 |
| Antigen Species | Human |
| Immunogen | Human PLA2G15 recombinant protein |
| Expression System | E.coli |
| Conjugation | Un-conjugated |
| Protein Full Name | Phospholipase A2 group XV |
| Alternate Names | PLA2G15; Phospholipase A2 Group XV; LLPL; GXVPLA2; LYPLA3; Lysophospholipase 3 (Lysosomal Phospholipase A2); Lysosomal Phospholipase A And Acyltransferase; LCAT-Like Lysophospholipase; Lysosomal Phospholipase A2; 1-O-Acylceramide Synthase; LPLA2; ACS; Phospholipase A2, Group XV; Group XV Phospholipase A2; Lysophospholipase 3; EC 3.1.1.32; EC 2.3.1.43; EC 3.1.1.5; EC 2.3.1.- ; EC 3.1.1.4 |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity purified with Immunogen. |
| Buffer | 0.9% NaCl, 0.2% Na2HPO4 and 4% Trehalose. |
| Stabilizer | 4% Trehalose |
| Concentration | 0.5 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | PLA2G15 |
| Gene Full Name | Phospholipase A2 Group XV |
| Background | Lysophospholipases are enzymes that act on biological membranes to regulate the multifunctional lysophospholipids. The protein encoded by this gene hydrolyzes lysophosphatidylcholine to glycerophosphorylcholine and a free fatty acid. This enzyme is present in the plasma and thought to be associated with high-density lipoprotein. A later paper contradicts the function of this gene. It demonstrates that this gene encodes a lysosomal enzyme instead of a lysophospholipase and has both calcium-independent phospholipase A2 and transacylase activities. |
| Function | Has dual calcium-independent phospholipase and O-acyltransferase activities with a potential role in glycerophospholipid homeostasis and remodeling of acyl groups of lipophilic alcohols present in acidic cellular compartments. |
| Cellular Localization | Lysosome, Membrane, Secreted |
| Calculated MW | 47 kDa |
| PTM | Disulfide bond, Glycoprotein |
