ARG40971
anti-PLA2G7 / Lp-PLA2 antibody
anti-PLA2G7 / Lp-PLA2 antibody for Flow cytometry,IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human
Overview
Product Description | Rabbit Polyclonal antibody recognizes PLA2G7 / Lp-PLA2 |
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Tested Reactivity | Hu |
Tested Application | FACS, IHC-P, WB |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | IgG |
Target Name | PLA2G7 / Lp-PLA2 |
Antigen Species | Human |
Immunogen | KLH-conjugated synthetic peptide corresponding to aa. 200-228 of Human PLA2G7. |
Conjugation | Un-conjugated |
Alternate Names | LDL-PLA; gVIIA-PLA2; LDL-PLA2; Group-VIIA phospholipase A2; 2-acetyl-1-alkylglycerophosphocholine esterase; EC 3.1.1.47; LDL-associated phospholipase A2; PAF 2-acylhydrolase; 2; PAF acetylhydrolase; PAFAH; Platelet-activating factor acetylhydrolase; PAFAD; 1-alkyl-2-acetylglycerophosphocholine esterase; LP-PLA2 |
Application Instructions
Application Suggestion |
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Application Note | IHC-P: Antigen Retrieval: Heat mediation was performed in Citrate buffer (pH 6.0). * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
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Positive Control | HL-60 |
Properties
Form | Liquid |
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Purification | Purification with Protein A and immunogen peptide. |
Buffer | PBS and 0.09% (W/V) Sodium azide. |
Preservative | 0.09% (W/V) Sodium azide. |
Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
Database Links |
Swiss-port # Q13093 Human Platelet-activating factor acetylhydrolase |
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Gene Symbol | PLA2G7 |
Gene Full Name | phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma) |
Background | The protein encoded by this gene is a secreted enzyme that catalyzes the degradation of platelet-activating factor to biologically inactive products. Defects in this gene are a cause of platelet-activating factor acetylhydrolase deficiency. Two transcript variants encoding the same protein have been found for this gene.[provided by RefSeq, Dec 2009] |
Function | Modulates the action of platelet-activating factor (PAF) by hydrolyzing the sn-2 ester bond to yield the biologically inactive lyso-PAF. Has a specificity for substrates with a short residue at the sn-2 position. It is inactive against long-chain phospholipids. [UniProt] |
Cellular Localization | Secreted, extracellular space. [UniProt] |
Calculated MW | 50 kDa |