ARG63088

anti-PLAP / Placental alkaline phosphatase antibody [H7E8]

anti-PLAP / Placental alkaline phosphatase antibody [H7E8] for ELISA,IHC-Frozen sections,IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human

Cancer antibody; Cell Biology and Cellular Response antibody; Controls and Markers antibody

Overview

Product Description Mouse Monoclonal antibody [H7E8] recognizes PLAP / Placental alkaline phosphatase
Tested Reactivity Hu
Tested Application ELISA, IHC-Fr, IHC-P, WB
Specificity The clone H7E8 recognizes throphoblast-derived membrane-associated enzyme alkaline phosphatase.
Host Mouse
Clonality Monoclonal
Clone H7E8
Isotype IgG2a
Target Name PLAP / Placental alkaline phosphatase
Immunogen Purified placental alkaline phosphatase.
Conjugation Un-conjugated
Alternate Names PALP; PLAP; EC 3.1.3.1; Alkaline phosphatase Regan isozyme; Placental alkaline phosphatase 1; PLAP-1; Alkaline phosphatase, placental type; ALP

Application Instructions

Application Suggestion
Tested Application Dilution
ELISAAssay-dependent
IHC-FrAssay-dependent
IHC-P10 µg/ml
WBAssay-dependent
Application Note * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.

Properties

Form Liquid
Purification Purified from hybridoma culture supernatant by protein A-affinity chromatography.
Purity > 95% (by SDS-PAGE)
Buffer PBS (pH 7.4) and 15 mM Sodium azide
Preservative 15 mM Sodium azide
Concentration 1 mg/ml
Storage Instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database Links

GeneID: 250 Human ALPP

Swiss-port # P05187 Human Alkaline phosphatase, placental type

Gene Symbol ALPP
Gene Full Name alkaline phosphatase, placental
Background The protein encoded by this gene is an alkaline phosphatase, a metalloenzyme that catalyzes the hydrolysis of phosphoric acid monoesters. It belongs to a multigene family composed of four alkaline phosphatase isoenzymes. The enzyme functions as a homodimer and has a catalytic site containing one magnesium and two zinc ions, which are required for its enzymatic function. The protein is primarily expressed in placental and endometrial tissue; however, strong ectopic expression has been detected in ovarian adenocarcinoma, serous cystadenocarcinoma, and other ovarian cancer cells. [provided by RefSeq, Jan 2015]
Research Area Cancer antibody; Cell Biology and Cellular Response antibody; Controls and Markers antibody
Calculated MW 58 kDa