ARG63088
anti-PLAP / Placental alkaline phosphatase antibody [H7E8]
anti-PLAP / Placental alkaline phosphatase antibody [H7E8] for ELISA,IHC-Frozen sections,IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human
Cancer antibody; Cell Biology and Cellular Response antibody; Controls and Markers antibody
Overview
Product Description | Mouse Monoclonal antibody [H7E8] recognizes PLAP / Placental alkaline phosphatase |
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Tested Reactivity | Hu |
Tested Application | ELISA, IHC-Fr, IHC-P, WB |
Specificity | The clone H7E8 recognizes throphoblast-derived membrane-associated enzyme alkaline phosphatase. |
Host | Mouse |
Clonality | Monoclonal |
Clone | H7E8 |
Isotype | IgG2a |
Target Name | PLAP / Placental alkaline phosphatase |
Immunogen | Purified placental alkaline phosphatase. |
Conjugation | Un-conjugated |
Alternate Names | PALP; PLAP; EC 3.1.3.1; Alkaline phosphatase Regan isozyme; Placental alkaline phosphatase 1; PLAP-1; Alkaline phosphatase, placental type; ALP |
Application Instructions
Application Suggestion |
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Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
Form | Liquid |
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Purification | Purified from hybridoma culture supernatant by protein A-affinity chromatography. |
Purity | > 95% (by SDS-PAGE) |
Buffer | PBS (pH 7.4) and 15 mM Sodium azide |
Preservative | 15 mM Sodium azide |
Concentration | 1 mg/ml |
Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
Database Links |
Swiss-port # P05187 Human Alkaline phosphatase, placental type |
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Gene Symbol | ALPP |
Gene Full Name | alkaline phosphatase, placental |
Background | The protein encoded by this gene is an alkaline phosphatase, a metalloenzyme that catalyzes the hydrolysis of phosphoric acid monoesters. It belongs to a multigene family composed of four alkaline phosphatase isoenzymes. The enzyme functions as a homodimer and has a catalytic site containing one magnesium and two zinc ions, which are required for its enzymatic function. The protein is primarily expressed in placental and endometrial tissue; however, strong ectopic expression has been detected in ovarian adenocarcinoma, serous cystadenocarcinoma, and other ovarian cancer cells. [provided by RefSeq, Jan 2015] |
Research Area | Cancer antibody; Cell Biology and Cellular Response antibody; Controls and Markers antibody |
Calculated MW | 58 kDa |