ARG43891
anti-PLEKHG5 antibody
anti-PLEKHG5 antibody for ELISA,ICC/IF,IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human
Overview
| Product Description | Rabbit Polyclonal antibody recognizes PLEKHG5 |
|---|---|
| Tested Reactivity | Hu |
| Tested Application | ELISA, ICC/IF, IHC-P, WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | PLEKHG5 |
| Antigen Species | Human |
| Immunogen | Human PLEKHG5 recombinant protein |
| Expression System | E.coli |
| Conjugation | Un-conjugated |
| Protein Full Name | Pleckstrin homology domain-containing family G member 5 |
| Alternate Names | PLEKHG5; Pleckstrin Homology And RhoGEF Domain Containing G5; GEF720; KIAA0720; Tech; Syx; Pleckstrin Homology Domain Containing, Family G (With RhoGef Domain) Member 5; Synectin-Binding Guanine Exchange Factor; PH Domain-Containing Family G Member 5; Guanine Nucleotide Exchange Factor 720; Novel PH Domain-Containing Protein; NFkB Activating Protein; CMTRIC; DSMA4 |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity purified with Immunogen. |
| Buffer | 0.9% NaCl, 0.2% Na2HPO4 and 4% Trehalose. |
| Stabilizer | 4% Trehalose |
| Concentration | 0.5 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links |
Swiss-port # O94827 Human Pleckstrin homology domain-containing family G member 5 |
|---|---|
| Gene Symbol | PLEKHG5 |
| Gene Full Name | Pleckstrin Homology And RhoGEF Domain Containing G5 |
| Background | This gene encodes a protein that activates the nuclear factor kappa B (NFKB1) signaling pathway. Mutations in this gene are associated with autosomal recessive distal spinal muscular atrophy. Multiple transcript variants encoding different isoforms have been found for this gene. |
| Function | Functions as a guanine exchange factor (GEF) for RAB26 and thus regulates autophagy of synaptic vesicles in axon terminal of motoneurons. |
| Cellular Localization | Cell junction, Cell membrane, Cell projection, Cytoplasm, Membrane |
| Calculated MW | 111 kDa |
| PTM | Phosphoprotein |
