ARG40941

anti-PLSCR1 antibody

anti-PLSCR1 antibody for Western blot,ICC/IF and Human

Overview

Product Description Rabbit Polyclonal antibody recognizes PLSCR1
Tested Reactivity Hu
Tested Application ICC/IF, WB
Host Rabbit
Clonality Polyclonal
Isotype IgG
Target Name PLSCR1
Antigen Species Human
Immunogen Recombinant fusion protein corresponding to aa. 1-318 of Human PLSCR1 (NP_066928.1).
Conjugation Un-conjugated
Alternate Names Phospholipid scramblase 1; Erythrocyte phospholipid scramblase; PL scramblase 1; Ca; MmTRA1b; MMTRA1B; 2+

Application Instructions

Application Suggestion
Tested Application Dilution
ICC/IF1:50 - 1:200
WB1:500 - 1:2000
Application Note * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
Positive Control THP-1
Observed Size 35 kDa

Properties

Form Liquid
Purification Affinity purified.
Buffer PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol.
Preservative 0.02% Sodium azide
Stabilizer 50% Glycerol
Storage Instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database Links

GeneID: 5359 Human PLSCR1

Swiss-port # O15162 Human Phospholipid scramblase 1

Gene Symbol PLSCR1
Gene Full Name phospholipid scramblase 1
Function May mediate accelerated ATP-independent bidirectional transbilayer migration of phospholipids upon binding calcium ions that results in a loss of phospholipid asymmetry in the plasma membrane. May play a central role in the initiation of fibrin clot formation, in the activation of mast cells and in the recognition of apoptotic and injured cells by the reticuloendothelial system.

May play a role in the antiviral response of interferon (IFN) by amplifying and enhancing the IFN response through increased expression of select subset of potent antiviral genes. May contribute to cytokine-regulated cell proliferation and differentiation. [UniProt]
Cellular Localization Cell membrane; Single-pass type II membrane protein. Membrane; Lipid-anchor; Cytoplasmic side. Nucleus. [UniProt]
Calculated MW 35 kDa