ARG43892
anti-PLVAP antibody
anti-PLVAP antibody for ELISA,Flow cytometry,Western blot and Human
Overview
| Product Description | Rabbit Polyclonal antibody recognizes PLVAP |
|---|---|
| Tested Reactivity | Hu |
| Tested Application | ELISA, FACS, WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | PLVAP |
| Antigen Species | Human |
| Immunogen | Human PLVAP recombinant protein |
| Expression System | E.coli |
| Conjugation | Un-conjugated |
| Protein Full Name | Plasmalemma vesicle-associated protein |
| Alternate Names | PLVAP; Plasmalemma Vesicle Associated Protein; PV-1; FELS; PV1; Gp68; Fenestrated-Endothelial Linked Structure Protein; PV-1 Protein; Fenestrated Endothelial-Linked Structure Protein; Plasmalemma Vesicle-Associated Protein; Plasmalemma Vesicle Protein 1; DIAR10 |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity purified with Immunogen. |
| Buffer | 0.9% NaCl, 0.2% Na2HPO4 and 4% Trehalose. |
| Stabilizer | 4% Trehalose |
| Concentration | 0.5 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links |
Swiss-port # Q9BX97 Human Plasmalemma vesicle-associated protein |
|---|---|
| Gene Symbol | PLVAP |
| Gene Full Name | Plasmalemma Vesicle Associated Protein |
| Background | Predicted to enable identical protein binding activity. Involved in MAPK cascade; positive regulation of cellular extravasation; and tumor necrosis factor-mediated signaling pathway. Located in cell surface. Colocalizes with caveola. Implicated in congenital diarrhea. |
| Function | Endothelial cell-specific membrane protein involved in the formation of the diaphragms that bridge endothelial fenestrae. It is also required for the formation of stomata of caveolae and transendothelial channels. Functions in microvascular permeability, endothelial fenestrae contributing to the passage of water and solutes and regulating transcellular versus paracellular flow in different organs. Plays a specific role in embryonic development. |
| Cellular Localization | Cell membrane, Cytoplasm, Membrane |
| Calculated MW | 51 kDa |
| PTM | Glycoprotein |
