ARG62601
anti-PMP22 antibody [20-14]
anti-PMP22 antibody [20-14] for Western blot and Human
Controls and Markers antibody; Neuroscience antibody
Overview
| Product Description | Mouse Monoclonal antibody [20-14] recognizes PMP22 |
|---|---|
| Tested Reactivity | Hu |
| Tested Application | WB |
| Host | Mouse |
| Clonality | Monoclonal |
| Clone | 20-14 |
| Isotype | IgM |
| Target Name | PMP22 |
| Antigen Species | Human |
| Immunogen | Synthetic peptide - amino acids 118-132 of Human PMP-22 |
| Conjugation | Un-conjugated |
| Alternate Names | HNPP; Peripheral myelin protein 22; HMSNIA; CMT1E; DSS; CMT1A; GAS-3; Sp110; PMP-22; Growth arrest-specific protein 3 |
Application Instructions
| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
|---|
Properties
| Form | Liquid |
|---|---|
| Purification | Protein A affinity purified |
| Buffer | PBS (pH 7.2), 0.2% BSA and 0.09% Sodium azide |
| Preservative | 0.09% Sodium azide |
| Stabilizer | 0.2% BSA |
| Concentration | 0.2 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | PMP22 |
| Gene Full Name | peripheral myelin protein 22 |
| Background | This gene encodes an integral membrane protein that is a major component of myelin in the peripheral nervous system. Studies suggest two alternately used promoters drive tissue-specific expression. Various mutations of this gene are causes of Charcot-Marie-Tooth disease Type IA, Dejerine-Sottas syndrome, and hereditary neuropathy with liability to pressure palsies. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013] |
| Function | Might be involved in growth regulation, and in myelinization in the peripheral nervous system. [UniProt] |
| Research Area | Controls and Markers antibody; Neuroscience antibody |
| Calculated MW | 18 kDa |
