ARG57043

anti-PMVK antibody [21C10]

anti-PMVK antibody [21C10] for Flow cytometry,Western blot and Human

Overview

Product Description Mouse Monoclonal antibody [21C10] recognizes PMVK
Tested Reactivity Hu
Tested Application FACS, WB
Host Mouse
Clonality Monoclonal
Clone 21C10
Isotype IgG2a, kappa
Target Name PMVK
Antigen Species Human
Immunogen Recombinant fragment around aa. 1-192 of Human PMVK.
Conjugation Un-conjugated
Alternate Names PMKase; PMKASE; hPMK; PMKA; HUMPMKI; EC 2.7.4.2; Phosphomevalonate kinase; PMK

Application Instructions

Application Suggestion
Tested Application Dilution
FACSAssay-dependent
WBAssay-dependent
Application Note * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.

Properties

Form Liquid
Purification Purification with Protein A.
Buffer PBS (pH 7.4), 0.02% Sodium azide and 10% Glycerol.
Preservative 0.02% Sodium azide
Stabilizer 10% Glycerol
Concentration 1 mg/ml
Storage Instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database Links

GeneID: 10654 Human PMVK

Swiss-port # Q15126 Human Phosphomevalonate kinase

Gene Symbol PMVK
Gene Full Name phosphomevalonate kinase
Background This gene encodes a peroxisomal enzyme that catalyzes the conversion of mevalonate 5-phosphate into mevalonate 5-diphosphate, the fifth reaction of the cholesterol biosynthetic pathway. Studies in rat show that the message level and the enzyme activity of this protein is regulated by sterol, and that this regulation is coordinated with 3-hydroxy-3-methylglutaryl coenzyme A reductase, the rate-limiting enzyme of cholesterol biosynthesis. [provided by RefSeq, Sep 2011]
Calculated MW 22 kDa