ARG55657

anti-POLD2 antibody

anti-POLD2 antibody for Western blot and Human,Mouse

Overview

Product Description Rabbit Polyclonal antibody recognizes POLD2
Tested Reactivity Hu, Ms
Predict Reactivity Rat
Tested Application WB
Host Rabbit
Clonality Polyclonal
Isotype IgG
Target Name POLD2
Antigen Species Human
Immunogen Recombinant protein of human POLD2
Conjugation Un-conjugated
Alternate Names DNA polymerase delta subunit 2; DNA polymerase delta subunit p50; EC 2.7.7.7

Application Instructions

Application Suggestion
Tested Application Dilution
WB1:500 - 1:2000
Application Note * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
Positive Control HL-60
Observed Size ~ 51 kDa

Properties

Form Liquid
Purification Affinity purification with immunogen.
Buffer PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol.
Preservative 0.02% Sodium azide
Stabilizer 50% Glycerol
Storage Instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database Links

GeneID: 18972 Mouse POLD2

GeneID: 5425 Human POLD2

Swiss-port # O35654 Mouse DNA polymerase delta subunit 2

Swiss-port # P49005 Human DNA polymerase delta subunit 2

Gene Symbol POLD2
Gene Full Name polymerase (DNA directed), delta 2, accessory subunit
Background This gene encodes the 50-kDa catalytic subunit of DNA polymerase delta. DNA polymerase delta possesses both polymerase and 3' to 5' exonuclease activity and plays a critical role in DNA replication and repair. The encoded protein is required for the stimulation of DNA polymerase delta activity by the processivity cofactor proliferating cell nuclear antigen (PCNA). Expression of this gene may be a marker for ovarian carcinomas. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is located on the long arm of chromosome 5. [provided by RefSeq, Mar 2012]
Function The function of the small subunit is not yet clear. [UniProt]
Calculated MW 51 kDa