ARG40094
anti-POMGnT2 / GTDC2 antibody
anti-POMGnT2 / GTDC2 antibody for Western blot and Human,Mouse
Overview
| Product Description | Rabbit Polyclonal antibody recognizes POMGnT2 / GTDC2 |
|---|---|
| Tested Reactivity | Hu, Ms |
| Tested Application | WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | POMGnT2 / GTDC2 |
| Antigen Species | Human |
| Immunogen | Recombinant fusion protein corresponding to aa. 160-340 of Human POMGnT2 / GTDC2 (NP_116195.2). |
| Conjugation | Un-conjugated |
| Alternate Names | Extracellular O-linked N-acetylglucosamine transferase-like; EC 2.4.1.-; Glycosyltransferase-like domain-containing protein 2; AGO61; POMGnT2; MDDGA8; GTDC2; C3orf39; Protein O-linked-mannose beta-1,4-N-acetylglucosaminyltransferase 2 |
Application Instructions
| Application Suggestion |
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|---|---|---|---|---|---|
| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||
| Positive Control | Mouse pancreas and A549 | ||||
| Observed Size | 75 kDa |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity purified. |
| Buffer | PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol. |
| Preservative | 0.02% Sodium azide |
| Stabilizer | 50% Glycerol |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links |
Swiss-port # Q8BW41 Mouse Protein O-linked-mannose beta-1,4-N-acetylglucosaminyltransferase 2 Swiss-port # Q8NAT1 Human Protein O-linked-mannose beta-1,4-N-acetylglucosaminyltransferase 2 |
|---|---|
| Gene Symbol | POMGNT2 |
| Gene Full Name | protein O-linked mannose N-acetylglucosaminyltransferase 2 (beta 1,4-) |
| Background | This gene encodes a protein with glycosyltransferase activity although its function is not currently known. [provided by RefSeq, Sep 2012] |
| Function | O-linked mannose beta-1,4-N-acetylglucosaminyltransferase that tranfers UDP-N-acetyl-D-glucosamine to the 4-position of the mannose to generate N-acetyl-D-glucosamine-beta-1,4-O-D-mannosylprotein. Involved in the biosynthesis of the phosphorylated O-mannosyl trisaccharide (N-acetylgalactosamine-beta-3-N-acetylglucosamine-beta-4-(phosphate-6-)mannose), a carbohydrate structure present in alpha-dystroglycan (DAG1), which is required for binding laminin G-like domain-containing extracellular proteins with high affinity. [UniProt] |
| Cellular Localization | Endoplasmic reticulum membrane; Single-pass type II membrane protein. [UniProt] |
| Calculated MW | 67 kDa |
