ARG43948
anti-POMP antibody
anti-POMP antibody for ELISA,Flow cytometry,Western blot and Human
Overview
| Product Description | Rabbit Polyclonal antibody recognizes POMP |
|---|---|
| Tested Reactivity | Hu |
| Tested Application | ELISA, FACS, WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | POMP |
| Antigen Species | Human |
| Immunogen | Human POMP recombinant protein |
| Expression System | E.coli |
| Conjugation | Un-conjugated |
| Protein Full Name | Proteasome maturation protein |
| Alternate Names | POMP; Proteasome Maturation Protein; UMP1; Proteassemblin; C13orf12; HSPC014; Voltage-Gated K Channel Beta Subunit 4.1; Protein UMP1 Homolog; HUMP1; Voltage-Gated Potassium Channel Beta Subunit 4.1; Chromosome 13 Open Reading Frame 12; 2510048O06Rik; PNAS-110; PRAAS2 |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity purified with Immunogen. |
| Buffer | 0.9% NaCl, 0.2% Na2HPO4 and 4% Trehalose. |
| Stabilizer | 4% Trehalose |
| Concentration | 0.5 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | POMP |
| Gene Full Name | Proteasome Maturation Protein |
| Background | The protein encoded by this gene is a molecular chaperone that binds 20S preproteasome components and is essential for 20S proteasome formation. The 20S proteasome is the proteolytically active component of the 26S proteasome complex. The encoded protein is degraded before the maturation of the 20S proteasome is complete. A variant in the 5' UTR of this gene has been associated with KLICK syndrome, a rare skin disorder. |
| Function | Molecular chaperone essential for the assembly of standard proteasomes and immunoproteasomes. Degraded after completion of proteasome maturation. Mediates the association of 20S preproteasome with the endoplasmic reticulum. |
| Cellular Localization | Cytoplasm, Endoplasmic reticulum, Membrane, Microsome, Nucleus |
| Calculated MW | 16 kDa |
| PTM | Isopeptide bond, Ubl conjugation |
