ARG44898
anti-PPP1R14D antibody
anti-PPP1R14D antibody for IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human
Overview
| Product Description | Mouse Monoclonal antibody recognizes PPP1R14D |
|---|---|
| Tested Reactivity | Hu |
| Tested Application | IHC-P, WB |
| Host | Mouse |
| Clonality | Monoclonal |
| Isotype | IgG1 |
| Target Name | PPP1R14D |
| Antigen Species | Human |
| Epitope | MLSSSPASCT SPSPDGENPC KKVHWASGRR RTSSTDSESK SHPDSSKIPR SRRPSRLTVK YDRGQLQRWL EMEQWVDAQV QELFQDQATP SEPEIDLEAL MDLSTEEQKT QLEAILGNCP RPTEAFISEL LSQLKKLRRL SRPQK |
| Conjugation | Un-conjugated |
| Alternate Names | PPP1R14D; Protein Phosphatase 1 Regulatory Inhibitor Subunit 14D; GBPI-1; CPI17-Like; Gastrointestinal And Brain-Specific PP1-Inhibitory Protein 1; Protein Phosphatase 1 Regulatory Subunit 14D; Gut And Brain Phosphatase Inhibitor 1; PKC-Dependent PP1 Inhibitory Protein; MGC119014; MGC119016; FLJ20251; Protein Phosphatase 1, Regulatory (Inhibitor) Subunit 14D; GBPI1; GBPI |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Protein A purified. |
| Buffer | PBS with 0.09% sodium azide |
| Preservative | 0.09% sodium azide |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Gene Symbol | PPP1R14D |
|---|---|
| Gene Full Name | Protein Phosphatase 1 Regulatory Inhibitor Subunit 14D |
| Background | Protein phosphatase-1 (PP1; see MIM 176875) is a major cellular phosphatase that reverses serine/threonine protein phosphorylation. PPP1R14D is a PP1 inhibitor that itself is regulated by phosphorylation (Liu et al., 2004 [PubMed 12974676]).[supplied by OMIM, Feb 2010] |
| Function | Inhibitor of PPP1CA. Has inhibitory activity only when phosphorylated, creating a molecular switch for regulating the phosphorylation status of PPP1CA substrates and smooth muscle contraction. [Uniprot] |
| Cellular Localization | Cytoplasm. [Uniprot] |
| Calculated MW | 17 kDa |
| PTM | Phosphoprotein. [Uniprot] |
