ARG40237
anti-PPP2R3B antibody
anti-PPP2R3B antibody for Western blot and Human,Mouse
Overview
| Product Description | Rabbit Polyclonal antibody recognizes PPP2R3B |
|---|---|
| Tested Reactivity | Hu, Ms |
| Tested Application | WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | PPP2R3B |
| Antigen Species | Human |
| Immunogen | Recombinant fusion protein corresponding to aa. 356-575 of Human PPP2R3B (NP_037371.2). |
| Conjugation | Un-conjugated |
| Alternate Names | PPP2R3L; PR48; PPP2R3LY; Serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit beta; Protein phosphatase 2A 48 kDa regulatory subunit; NYREN8; PP2A subunit B isoform PR48 |
Application Instructions
| Application Suggestion |
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|---|---|---|---|---|---|
| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||
| Positive Control | SKOV3 and SW620 | ||||
| Observed Size | ~ 70 kDa |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity purified. |
| Buffer | PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol. |
| Preservative | 0.02% Sodium azide |
| Stabilizer | 50% Glycerol |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links |
Swiss-port # Q9Y5P8 Human Serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit bet |
|---|---|
| Gene Symbol | PPP2R3B |
| Gene Full Name | protein phosphatase 2, regulatory subunit B'', beta |
| Background | Protein phosphatase 2 (formerly named type 2A) is one of the four major Ser/Thr phosphatases and is implicated in the negative control of cell growth and division. Protein phosphatase 2 holoenzymes are heterotrimeric proteins composed of a structural subunit A, a catalytic subunit C, and a regulatory subunit B. The regulatory subunit is encoded by a diverse set of genes that have been grouped into the B/PR55, B'/PR61, and B''/PR72 families. These different regulatory subunits confer distinct enzymatic specificities and intracellular localizations to the holozenzyme. The product of this gene belongs to the B'' family. The B'' family has been further divided into subfamilies. The product of this gene belongs to the beta subfamily of regulatory subunit B''. [provided by RefSeq, Apr 2010] |
| Function | The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. [UniProt] |
| Cellular Localization | Nucleus. [UniProt] |
| Calculated MW | 65 kDa |
Images (1) Click the Picture to Zoom In
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ARG40237 anti-PPP2R3B antibody WB image
Western blot: 25 µg of SKOV3 and SW620 cell lysates stained with ARG40237 anti-PPP2R3B antibody at 1:1000 dilution.
