ARG43929
anti-PPP3CA antibody
anti-PPP3CA antibody for ELISA,Flow cytometry,ICC/IF,Western blot and Human,Rat
Overview
| Product Description | Rabbit Polyclonal antibody recognizes PPP3CA |
|---|---|
| Tested Reactivity | Hu, Rat |
| Tested Application | ELISA, FACS, ICC/IF, WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | PPP3CA |
| Antigen Species | Human |
| Immunogen | Human PPP3CA recombinant protein |
| Expression System | E.coli |
| Conjugation | Un-conjugated |
| Protein Full Name | Protein phosphatase 3 catalytic subunit alpha |
| Alternate Names | PPP3CA; Protein Phosphatase 3 Catalytic Subunit Alpha; Calcineurin A Alpha; PPP2B; CALNA; CNA1; CAM-PRP Catalytic Subunit; EC 3.1.3.16; CNA Alpha; CALN; Protein Phosphatase 3 (Formerly 2B), Catalytic Subunit, Alpha Isoform (Calcineurin A Alpha); Serine/Threonine-Protein Phosphatase 2B Catalytic Subunit Alpha Isoform; Protein Phosphatase 3 (Formerly 2B), Catalytic Subunit, Alpha Isoform; Protein Phosphatase 2B, Catalytic Subunit, Alpha Isoform; Calmodulin-Dependent Calcineurin A Subunit Alpha Isoform; Protein Phosphatase 3, Catalytic Subunit, Alpha Isozyme; Protein Phosphatase 3 Catalytic Subunit Alpha Isozyme; ACCIID; CALNA1; IECEE1; DEE91; IECEE; CCN1; CNA |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity purified with Immunogen. |
| Buffer | 0.9% NaCl, 0.2% Na2HPO4 and 4% Trehalose. |
| Stabilizer | 4% Trehalose |
| Concentration | 0.5 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links |
Swiss-port # P63329 Rat Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform Swiss-port # Q08209 Human Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform |
|---|---|
| Gene Symbol | PPP3CA |
| Gene Full Name | Protein Phosphatase 3 Catalytic Subunit Alpha |
| Background | Enables several functions, including ATPase binding activity; calmodulin binding activity; and calmodulin-dependent protein phosphatase activity. Involved in several processes, including calcineurin-NFAT signaling cascade; peptidyl-serine dephosphorylation; and response to calcium ion. Located in several cellular components, including cytosol; dendritic spine; and nucleoplasm. Part of calcineurin complex. Colocalizes with cytoplasmic side of plasma membrane. Implicated in developmental and epileptic encephalopathy 91. Biomarker of focal segmental glomerulosclerosis and schizophrenia. |
| Function | Calcium-dependent, calmodulin-stimulated protein phosphatase which plays an essential role in the transduction of intracellular Ca2+-mediated signals. |
| Cellular Localization | Cell membrane, Cell projection, Cytoplasm, Membrane, Synapse |
| Calculated MW | 59 kDa |
| PTM | Acetylation, Nitration, Phosphoprotein |
Images (4) Click the Picture to Zoom In
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ARG43929 anti-PPP3CA antibody ICC/IF image
Immunofluorescence: U2OS cells stained with ARG43929 anti-PPP3CA antibody at 5 μg/ml dilution.
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ARG43929 anti-PPP3CA antibody WB image
Western blot: HeLa and U-87MG stained with ARG43929 anti-PPP3CA antibody at 0.5 μg/mL dilution.
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ARG43929 anti-PPP3CA antibody FACS image
Flow Cytometry: SiHa cells stained with ARG43929 anti-PPP3CA antibody (blue) at 1 μg/1x10^6 cells dilution.
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ARG43929 anti-PPP3CA antibody WB image
Western blot: C6 stained with ARG43929 anti-PPP3CA antibody at 0.5 μg/mL dilution.
