ARG43972
anti-PRAM1 antibody
anti-PRAM1 antibody for ELISA,Flow cytometry,Western blot and Human
Overview
| Product Description | Rabbit Polyclonal antibody recognizes PRAM1 |
|---|---|
| Tested Reactivity | Hu |
| Tested Application | ELISA, FACS, WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | PRAM1 |
| Antigen Species | Human |
| Immunogen | Human PRAM1 recombinant protein |
| Expression System | E.coli |
| Conjugation | Un-conjugated |
| Protein Full Name | PML-RARA-regulated adapter molecule 1 |
| Alternate Names | PRAM1; PML-RARA Regulated Adaptor Molecule 1; PML-RAR; PML-RARA-Regulated Adapter Molecule 1; PRAM-1; PRAM; PML-RARA Target Gene Encoding An Adaptor Molecule-1 |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity purified with Immunogen. |
| Buffer | 0.9% NaCl, 0.2% Na2HPO4 and 4% Trehalose. |
| Stabilizer | 4% Trehalose |
| Concentration | 0.5 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links |
Swiss-port # Q96QH2 Human PML-RARA-regulated adapter molecule 1 |
|---|---|
| Gene Symbol | PRAM1 |
| Gene Full Name | PML-RARA Regulated Adaptor Molecule 1 |
| Background | The protein encoded by this gene is similar to FYN binding protein (FYB/SLAP-130), an adaptor protein involved in T cell receptor mediated signaling. This gene is expressed and regulated during normal myelopoiesis. The expression of this gene is induced by retinoic acid and is inhibited by the expression of PML-RARalpha, a fusion protein of promyelocytic leukemia (PML) and the retinoic acid receptor-alpha (RARalpha). |
| Function | May be involved in myeloid differentiation. May be involved in integrin signaling in neutrophils. Binds to PtdIns4P. |
| Calculated MW | 74 kDa |
| PTM | Phosphoprotein |
