ARG42782

anti-PROK1 / EG-VEGF antibody

anti-PROK1 / EG-VEGF antibody for Western blot,Flow cytometry and Human,Mouse

Overview

Product Description Rabbit Polyclonal antibody recognizes PROK1 / EG-VEGF
Tested Reactivity Hu, Ms
Tested Application FACS, WB
Host Rabbit
Clonality Polyclonal
Isotype IgG
Target Name PROK1 / EG-VEGF
Antigen Species Human
Immunogen Synthetic peptide derived from Human PROK1 / EG-VEGF.
Conjugation Un-conjugated
Alternate Names PK1; Endocrine-gland-derived vascular endothelial growth factor; Prokineticin-1; PRK1; EG-VEGF; Mambakine; EGVEGF

Application Instructions

Application Suggestion
Tested Application Dilution
FACS1:50
WB1:500 - 1:2000
Application Note * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
Positive Control Raw264.7
Observed Size ~ 14 kDa

Properties

Form Liquid
Purification Affinity purified.
Buffer PBS (pH 7.4), 150 mM NaCl, 0.02% Sodium azide and 50% Glycerol.
Preservative 0.02% Sodium azide
Stabilizer 50% Glycerol
Storage Instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database Links

GeneID: 246691 Mouse PROK1

GeneID: 84432 Human PROK1

Swiss-port # P58294 Human Prokineticin-1

Swiss-port # Q14A28 Mouse Prokineticin-1

Gene Symbol PROK1
Gene Full Name prokineticin 1
Background The protein encoded by this gene induces proliferation, migration, and fenestration (the formation of membrane discontinuities) in capillary endothelial cells derived from endocrine glands. It has little or no effect on a variety of other endothelial and non-endothelial cell types. Its expression is restricted to the steroidogenic glands (ovary, testis, adrenal, and placenta), is induced by hypoxia, and often complementary to the expression of vascular endothelial growth factor (VEGF), suggesting that these molecules function in a coordinated manner. [provided by RefSeq, Sep 2011]
Function Potently contracts gastrointestinal (GI) smooth muscle. Induces proliferation, migration and fenestration (the formation of membrane discontinuities) in capillary endothelial cells derived from endocrine glands. Has little or no effect on a variety of other endothelial and non-endothelial cell types. Induces proliferation and differentiation, but not migration, of enteric neural crest cells. Directly influences neuroblastoma progression by promoting the proliferation and migration of neuroblastoma cells. Positively regulates PTGS2 expression and prostaglandin synthesis. May play a role in placentation. May play a role in normal and pathological testis angiogenesis. [UniProt]
Cellular Localization Secreted. [UniProt]
Calculated MW 12 kDa