ARG55476

anti-PSMA4 antibody

anti-PSMA4 antibody for ICC/IF,Western blot and Human,Monkey,Mouse,Rat

Cell Biology and Cellular Response antibody

Overview

Product Description Rabbit Polyclonal antibody recognizes PSMA4
Tested Reactivity Hu, Ms, Rat, Mk
Tested Application ICC/IF, WB
Host Rabbit
Clonality Polyclonal
Isotype IgG
Target Name PSMA4
Antigen Species Human
Immunogen Recombinant protein of Human PSMA4
Conjugation Un-conjugated
Alternate Names Proteasome component C9; PSC9; Proteasome subunit alpha type-4; HC9; Proteasome subunit L; HsT17706; Multicatalytic endopeptidase complex subunit C9; Macropain subunit C9; EC 3.4.25.1

Application Instructions

Application Suggestion
Tested Application Dilution
ICC/IF1:50 - 1:200
WB1:500 - 1:2000
Application Note * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
Positive Control Jurkat, Mouse liver and PC-12
Observed Size ~ 30 kDa

Properties

Form Liquid
Purification Affinity purification with immunogen.
Buffer PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol
Preservative 0.02% Sodium azide
Stabilizer 50% Glycerol
Storage Instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database Links

GeneID: 26441 Mouse PSMA4

GeneID: 29671 Rat PSMA4

GeneID: 5685 Human PSMA4

Gene Symbol PSMA4
Gene Full Name proteasome (prosome, macropain) subunit, alpha type, 4
Background The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the peptidase T1A family, that is a 20S core alpha subunit. Three alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Function The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity. [UniProt]
Research Area Cell Biology and Cellular Response antibody
Calculated MW 29 kDa