ARG56225

anti-PSMD13 antibody

anti-PSMD13 antibody for Western blot,IHC-Formalin-fixed paraffin-embedded sections,Flow cytometry and Human

Overview

Product Description Rabbit Polyclonal antibody recognizes PSMD13
Tested Reactivity Hu
Predict Reactivity Ms, Rat, Chk
Tested Application FACS, IHC-P, WB
Host Rabbit
Clonality Polyclonal
Isotype IgG
Target Name PSMD13
Antigen Species Human
Immunogen KLH-conjugated synthetic peptide corresponding to aa. 269-298 (C-terminal) of HHuman PSMD13.
Conjugation Un-conjugated
Alternate Names 26S proteasome regulatory subunit RPN9; HSPC027; 26S proteasome non-ATPase regulatory subunit 13; Rpn9; S11; 26S proteasome regulatory subunit S11; 26S proteasome regulatory subunit p40.5; p40.5

Application Instructions

Application Suggestion
Tested Application Dilution
FACS1:10 - 1:50
IHC-P1:50 - 1:100
WB1:1000
Application Note * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
Positive Control Y79

Properties

Form Liquid
Purification Purification with Protein A and immunogen peptide
Buffer PBS and 0.09% (W/V) Sodium azide.
Preservative 0.09% (W/V) Sodium azide.
Storage Instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database Links

GeneID: 5719 Human PSMD13

Swiss-port # Q9UNM6 Human 26S proteasome non-ATPase regulatory subunit 13

Gene Symbol PSMD13
Gene Full Name proteasome (prosome, macropain) 26S subunit, non-ATPase, 13
Background The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a non-ATPase subunit of the 19S regulator. Two transcripts encoding different isoforms have been described. [provided by RefSeq, Jul 2008]
Function Acts as a regulatory subunit of the 26S proteasome which is involved in the ATP-dependent degradation of ubiquitinated proteins. [UniProt]
Calculated MW 43 kDa