ARG44565

anti-PTCD1 antibody

anti-PTCD1 antibody for Flow cytometry,IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Mouse,Rat

Overview

Product Description Rabbit Polyclonal antibody recognizes PTCD1
Tested Reactivity Hu, Ms, Rat
Tested Application FACS, IHC-P, WB
Host Rabbit
Clonality Polyclonal
Isotype IgG
Target Name PTCD1
Antigen Species Human
Immunogen Human PTCD1 recombinant protein (aa. sequence: D203-L601).
Conjugation Un-conjugated
Alternate Names PTCD1; Pentatricopeptide Repeat Domain 1; KIAA0632; Pentatricopeptide Repeat-Containing Protein 1, Mitochondrial

Application Instructions

Application Suggestion
Tested Application Dilution
FACS1-3 µg/10^6 cells
IHC-P2-5 µg/ml
WB0.25-0.5 µg/ml
Application Note * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.

Properties

Form Liquid
Purification Affinity purified.
Buffer 0.2% Na2HPO4, 0.9% NaCl and 4% Trehalose.
Preservative 4% Trehalose
Storage Instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database Links

GeneID: 26024 Human PTCD1

GeneID: 304278 Rat PTCD1

GeneID: 71799 Mouse PTCD1

Gene Symbol PTCD1
Gene Full Name Pentatricopeptide Repeat Domain 1
Background This gene encodes a mitochondrial protein that binds leucine tRNAs and other mitochondrial RNAs and plays a role in the regulation of translation. Increased expression of this gene results in decreased mitochondrial leucine tRNA levels. Naturally occurring read-through transcription exists between upstream ATP5J2 (ATP synthase, H+ transporting, mitochondrial Fo complex, subunit F2) and this gene. [provided by RefSeq, Aug 2015]
Function Mitochondrial protein implicated in negative regulation of leucine tRNA levels, as well as negative regulation of mitochondria-encoded proteins and COX activity. Affects also the 3'-processing of mitochondrial tRNAs. [Uniprot]
Cellular Localization Mitochondrion. [Uniprot]
Calculated MW 79 kDa