ARG45096
anti-PTCH2 antibody
anti-PTCH2 antibody for Western blot and Human,Mouse
Overview
| Product Description | Rabbit Polyclonal antibody recognizes PTCH2 |
|---|---|
| Tested Reactivity | Hu, Ms |
| Tested Application | WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | PTCH2 |
| Antigen Species | Human |
| Immunogen | Synthetic peptide corresponding to amino acids from human PTCH2 protein |
| Conjugation | Un-conjugated |
| Alternate Names | PTCH2; Patched 2; Protein Patched Homolog 2; PTC2; Patched (Drosophila) Homolog 2; Patched Homolog 2 (Drosophila); Patched Homolog 2 |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Antigen Affinity Purified. |
| Buffer | PBS, 0.02% NaN3 |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | PTCH2 |
| Gene Full Name | Patched 2 |
| Background | This gene encodes a transmembrane receptor of the patched gene family. The encoded protein may function as a tumor suppressor in the hedgehog signaling pathway. Alterations in this gene have been associated with nevoid basal cell carcinoma syndrome, basal cell carcinoma, medulloblastoma, and susceptibility to congenital macrostomia. Alternatively spliced transcript variants have been described.[provided by RefSeq, Oct 2009] |
| Function | May have a role in epidermal development. May act as a receptor for Sonic hedgehog (SHH). [Uniprot] |
| Cellular Localization | Membrane. [Uniprot] |
| Calculated MW | 130 kDa |
| PTM | Glycoprotein. [Uniprot] |
