ARG64229

anti-PTF1A / PFT1-P48 antibody

anti-PTF1A / PFT1-P48 antibody for Western blot and Human,Mouse

Gene Regulation antibody; Neuroscience antibody

Overview

Product Description Goat Polyclonal antibody recognizes PTF1A / PFT1-P48
Tested Reactivity Hu, Ms
Predict Reactivity Dog, Rat, Zfsh
Tested Application WB
Host Goat
Clonality Polyclonal
Isotype IgG
Target Name PTF1A / PFT1-P48
Antigen Species Human
Immunogen C-WTDEKQLKEQN
Conjugation Un-conjugated
Alternate Names p48 DNA-binding subunit of transcription factor PTF1; bHLHa29; Pancreas transcription factor 1 subunit alpha; Pancreas-specific transcription factor 1a; Class A basic helix-loop-helix protein 29; PACA; bHLH transcription factor p48; PAGEN2; PTF1-p48

Application Instructions

Application Suggestion
Tested Application Dilution
WB0.5 - 2 µg/ml
Application Note WB: Recommend incubate at RT for 1h.
* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.

Properties

Form Liquid
Purification Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Buffer Tris saline (pH 7.3), 0.02% Sodium azide and 0.5% BSA
Preservative 0.02% Sodium azide
Stabilizer 0.5% BSA
Concentration 0.5 mg/ml
Storage Instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database Links

GeneID: 19213 Mouse PTF1A

GeneID: 256297 Human PTF1A

Swiss-port # Q7RTS3 Human Pancreas transcription factor 1 subunit alpha

Swiss-port # Q9QX98 Mouse Pancreas transcription factor 1 subunit alpha

Background This gene encodes a protein that is a component of the pancreas transcription factor 1 complex (PTF1) and is known to have a role in mammalian pancreatic development. The protein plays a role in determining whether cells allocated to the pancreatic buds continue towards pancreatic organogenesis or revert back to duodenal fates. The protein is thought to be involved in the maintenance of exocrine pancreas-specific gene expression including elastase 1 and amylase. Mutations in this gene cause cerebellar agenesis and loss of expression is seen in ductal type pancreas cancers. [provided by RefSeq, Jul 2008]
Research Area Gene Regulation antibody; Neuroscience antibody
Calculated MW 35 kDa