ARG56485
anti-PTGFR antibody
anti-PTGFR antibody for Western blot and Human,Mouse,Rat,Bovine,Sheep
Overview
| Product Description | Rabbit Polyclonal antibody recognizes PTGFR |
|---|---|
| Tested Reactivity | Hu, Ms, Rat, Bov, Sheep |
| Tested Application | WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | PTGFR |
| Antigen Species | Mouse |
| Immunogen | Synthetic peptide around the N-terminal cytoplasmic region of Mouse PTGFR. |
| Conjugation | Un-conjugated |
| Alternate Names | FP; Prostanoid FP receptor; Prostaglandin F2-alpha receptor; PGF receptor; PGF2-alpha receptor |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity purification with immunogen. |
| Buffer | TBS (pH 7.4) and 5 mg/ml BSA. |
| Stabilizer | 5 mg/ml BSA |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | PTGFR |
| Gene Full Name | prostaglandin F receptor (FP) |
| Background | The protein encoded by this gene is member of the G-protein coupled receptor family. This protein is a receptor for prostaglandin F2-alpha (PGF2-alpha), which is known to be a potent luteolytic agent, and may also be involved in modulating intraocular pressure and smooth muscle contraction in uterus. Knockout studies in mice suggest that the interaction of PGF2-alpha with this receptor may initiate parturition in ovarian luteal cells and thus induce luteolysis. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] |
| Function | Receptor for prostaglandin F2-alpha (PGF2-alpha). The activity of this receptor is mediated by G proteins which activate a phosphatidylinositol-calcium second messenger system. Initiates luteolysis in the corpus luteum (By similarity). Isoforms 2 to 7 do not bind PGF2-alpha but are proposed to modulate signaling by participating in variant receptor complexes; heterodimers between isoform 1 and isoform 5 are proposed to be a receptor for prostamides including the synthetic analog bimatoprost. [UniProt] |
| Calculated MW | 40 kDa |
