ARG41470

anti-PTHR1 antibody

anti-PTHR1 antibody for Western blot,Immunoprecipitation and Human

Overview

Product Description Rabbit Polyclonal antibody recognizes PTHR1
Tested Reactivity Hu
Tested Application IP, WB
Host Rabbit
Clonality Polyclonal
Isotype IgG
Target Name PTHR1
Antigen Species Human
Immunogen Synthetic peptide of Human PTHR1.
Conjugation Un-conjugated
Alternate Names Parathyroid hormone/parathyroid hormone-related peptide receptor; PTH/PTHrP type I receptor; Parathyroid hormone 1 receptor; PTHR1; PTH/PTHr receptor; PFE; PTHR; PTH1 receptor

Application Instructions

Application Suggestion
Tested Application Dilution
IP1:50
WB1:500 - 1:2000
Application Note * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
Positive Control HeLa
Observed Size ~ 65 kDa

Properties

Form Liquid
Purification Affinity purified.
Buffer PBS (pH 7.4), 150 mM NaCl, 0.02% Sodium azide and 50% Glycerol.
Preservative 0.02% Sodium azide
Stabilizer 50% Glycerol
Storage Instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database Links

GeneID: 5745 Human PTH1R

Swiss-port # Q03431 Human Parathyroid hormone/parathyroid hormone-related peptide receptor

Gene Symbol PTH1R
Gene Full Name parathyroid hormone 1 receptor
Background The protein encoded by this gene is a member of the G-protein coupled receptor family 2. This protein is a receptor for parathyroid hormone (PTH) and for parathyroid hormone-like hormone (PTHLH). The activity of this receptor is mediated by G proteins which activate adenylyl cyclase and also a phosphatidylinositol-calcium second messenger system. Defects in this receptor are known to be the cause of Jansen's metaphyseal chondrodysplasia (JMC), chondrodysplasia Blomstrand type (BOCD), as well as enchodromatosis. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, May 2010]
Function This is a receptor for parathyroid hormone and for parathyroid hormone-related peptide. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase and also a phosphatidylinositol-calcium second messenger system. [UniProt]
Cellular Localization Cell membrane; Multi-pass membrane protein. [UniProt]
Calculated MW 66 kDa