ARG44005
anti-PYCR1 antibody
anti-PYCR1 antibody for ELISA,Flow cytometry,ICC/IF,IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human
Overview
| Product Description | Rabbit Polyclonal antibody recognizes PYCR1 |
|---|---|
| Tested Reactivity | Hu |
| Tested Application | ELISA, FACS, ICC/IF, IHC-P, WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | PYCR1 |
| Antigen Species | Human |
| Immunogen | Human PYCR1 recombinant protein |
| Expression System | E.coli |
| Conjugation | Un-conjugated |
| Protein Full Name | Pyrroline-5-carboxylate reductase 1, mitochondrial |
| Alternate Names | PYCR1; Pyrroline-5-Carboxylate Reductase 1; P5C; Pyrroline-5-Carboxylate Reductase 1, Mitochondrial; P5C Reductase 1; EC 1.5.1.2; Proliferation-Inducing Protein 45; ARCL2B; ARCL3B; P5CR 1; PIG45; PP222; P5CR; PRO3; PYCR |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity purified with Immunogen. |
| Buffer | 0.9% NaCl, 0.2% Na2HPO4 and 4% Trehalose. |
| Stabilizer | 4% Trehalose |
| Concentration | 0.5 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links |
Swiss-port # P32322 Human Pyrroline-5-carboxylate reductase 1, mitochondrial |
|---|---|
| Gene Symbol | PYCR1 |
| Gene Full Name | Pyrroline-5-Carboxylate Reductase 1 |
| Background | This gene encodes an enzyme that catalyzes the NAD(P)H-dependent conversion of pyrroline-5-carboxylate to proline. This enzyme may also play a physiologic role in the generation of NADP(+) in some cell types. The protein forms a homopolymer and localizes to the mitochondrion. Alternative splicing results in multiple transcript variants. |
| Function | Housekeeping enzyme that catalyzes the last step in proline biosynthesis. Can utilize both NAD and NADP, but has higher affinity for NAD. Involved in the cellular response to oxidative stress. |
| Cellular Localization | Mitochondrion |
| Calculated MW | 33 kDa |
| PTM | Acetylation, Phosphoprotein |
