ARG44281
anti-PanK4 (Thr63) antibody
anti-PanK4 (Thr63) antibody for Western blot and Mouse
Overview
| Product Description | Rabbit Polyclonal antibody recognizes PanK4 phospho (Thr63) |
|---|---|
| Tested Reactivity | Ms |
| Predict Reactivity | Hm, Rat |
| Tested Application | WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | PANK4 |
| Antigen Species | Mouse |
| Immunogen | Synthetic phospho-peptide |
| Conjugation | Un-conjugated |
| Alternate Names | PANK4; Pantothenate Kinase 4 (Inactive); Inactive Pantothenic Acid Kinase 4; 4'-Phosphopantetheine Phosphatase; FLJ10782; Pantothenic Acid Kinase 4; Pantothenate Kinase 4; EC 2.7.1.33; EC 3.1.3.-; CTRCT49; HPanK4 |
Application Instructions
| Application Suggestion |
|
||||
|---|---|---|---|---|---|
| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Antigen Affinity Purified |
| Buffer | 10 mM HEPES (pH 7.5), 150 mM NaCl, 50% Glycerol and 100 µg/ml BSA. |
| Stabilizer | 50% Glycerol and 100 µg/ml BSA |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | PANK4 |
| Gene Full Name | Pantothenate Kinase 4 |
| Background | This gene encodes a protein belonging to the pantothenate kinase family. Pantothenate kinase is a key regulatory enzyme in the biosynthesis of coenzyme A (CoA) in bacteria and mammalian cells. It catalyzes the first committed step in the universal biosynthetic pathway leading to CoA and is itself subject to regulation through feedback inhibition by CoA. This family member is most abundant in muscle but is expressed in all tissues. |
| Function | Phosphatase which shows a preference for 4'-phosphopantetheine and its oxidatively damaged forms (sulfonate or S-sulfonate), providing strong indirect evidence that the phosphatase activity pre-empts damage in the coenzyme A (CoA) pathway. |
| Cellular Localization | Cytoplasm |
| Calculated MW | 86 kDa |
| PTM | Acetylation, Nitration, Phosphoprotein |
