ARG65291
anti-Pex 1 antibody
anti-Pex 1 antibody for Western blot and Mouse,Rat
Signaling Transduction antibody
Overview
| Product Description | Goat Polyclonal antibody recognizes Pex 1 |
|---|---|
| Tested Reactivity | Ms, Rat |
| Predict Reactivity | Hu, Cow, Dog |
| Tested Application | WB |
| Host | Goat |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | Pex 1 |
| Antigen Species | Mouse |
| Immunogen | C-QAKESTFPKEGDAH |
| Conjugation | Un-conjugated |
| Alternate Names | Peroxisome biogenesis disorder protein 1; Peroxin-1; PBD1A; PBD1B; Peroxisome biogenesis factor 1; ZWS; ZWS1 |
Application Instructions
| Application Suggestion |
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|---|---|---|---|---|---|
| Application Note | WB: Recommend incubate at RT for 1h. * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Purified from goat serum by antigen affinity chromatography. |
| Buffer | Tris saline (pH 7.3), 0.02% Sodium azide and 0.5% BSA. |
| Preservative | 0.02% Sodium azide |
| Stabilizer | 0.5% BSA |
| Concentration | 0.5 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | Pex1 |
| Gene Full Name | peroxisomal biogenesis factor 1 |
| Background | This gene encodes a member of the AAA ATPase family, a large group of ATPases associated with diverse cellular activities. This protein is cytoplasmic but is often anchored to a peroxisomal membrane where it forms a heteromeric complex and plays a role in the import of proteins into peroxisomes and peroxisome biogenesis. Mutations in this gene have been associated with complementation group 1 peroxisomal disorders such as neonatal adrenoleukodystrophy, infantile Refsum disease, and Zellweger syndrome. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Sep 2013] |
| Function | Required for stability of PEX5 and protein import into the peroxisome matrix. Anchored by PEX26 to peroxisome membranes, possibly to form heteromeric AAA ATPase complexes required for the import of proteins into peroxisomes (By similarity). [UniProt] |
| Research Area | Signaling Transduction antibody |
| Calculated MW | 143 kDa |
