ARG56498
anti-Phospholipase A2 IIA antibody [SCACC353]
anti-Phospholipase A2 IIA antibody [SCACC353] for IHC-Formalin-fixed paraffin-embedded sections,Immunoprecipitation,Western blot and Human
Overview
| Product Description | Mouse Monoclonal antibody [SCACC353] recognizes Phospholipase A2 IIA |
|---|---|
| Tested Reactivity | Hu |
| Tested Application | IHC-P, IP, WB |
| Specificity | This antibody does not react to Human sPLA2 (Type V). |
| Host | Mouse |
| Clonality | Monoclonal |
| Clone | SCACC353 |
| Isotype | IgG1 |
| Target Name | Phospholipase A2 IIA |
| Antigen Species | Human |
| Immunogen | Human recombinant synovial Phospholipase A2 IIA. |
| Conjugation | Un-conjugated |
| Alternate Names | PLA2B; GIIC sPLA2; EC 3.1.1.4; Non-pancreatic secretory phospholipase A2; PLA2; MOM1; PLA2L; PLAS1; PLA2S; NPS-PLA2; Group IIA phospholipase A2; sPLA2; Phospholipase A2, membrane associated; Phosphatidylcholine 2-acylhydrolase 2A |
Application Instructions
| Application Suggestion |
|
||||||||
|---|---|---|---|---|---|---|---|---|---|
| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity purification with immunogen. |
| Buffer | PBS (pH 7.2), 0.02% Sodium azide, 50% Glycerol and 0.1% BSA. |
| Preservative | 0.02% Sodium azide |
| Stabilizer | 50% Glycerol and 0.1% BSA |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links |
Swiss-port # P14555 Human Phospholipase A2, membrane associated |
|---|---|
| Gene Symbol | PLA2G2A |
| Gene Full Name | phospholipase A2, group IIA (platelets, synovial fluid) |
| Background | The protein encoded by this gene is a member of the phospholipase A2 family (PLA2). PLA2s constitute a diverse family of enzymes with respect to sequence, function, localization, and divalent cation requirements. This gene product belongs to group II, which contains secreted form of PLA2, an extracellular enzyme that has a low molecular mass and requires calcium ions for catalysis. It catalyzes the hydrolysis of the sn-2 fatty acid acyl ester bond of phosphoglycerides, releasing free fatty acids and lysophospholipids, and thought to participate in the regulation of the phospholipid metabolism in biomembranes. Several alternatively spliced transcript variants with different 5' UTRs have been found for this gene.[provided by RefSeq, Sep 2009] |
| Function | Thought to participate in the regulation of the phospholipid metabolism in biomembranes including eicosanoid biosynthesis. Catalyzes the calcium-dependent hydrolysis of the 2-acyl groups in 3-sn-phosphoglycerides. [UniProt] |
| Calculated MW | 16 kDa |
