ARG58687
anti-Phospholipase D2 antibody
anti-Phospholipase D2 antibody for Western blot and Human,Mouse,Rat
Overview
| Product Description | Rabbit Polyclonal antibody recognizes Phospholipase D2 |
|---|---|
| Tested Reactivity | Hu, Ms, Rat |
| Tested Application | WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | Phospholipase D2 |
| Antigen Species | Human |
| Immunogen | Recombinant fusion protein corresponding to aa. 1-180 of Human Phospholipase D2 (NP_002654.3). |
| Conjugation | Un-conjugated |
| Alternate Names | Choline phosphatase 2; PLD1C; PLD 2; Phosphatidylcholine-hydrolyzing phospholipase D2; Phospholipase D2; EC 3.1.4.4; hPLD2 |
Application Instructions
| Application Suggestion |
|
||||
|---|---|---|---|---|---|
| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||
| Positive Control | BT474 | ||||
| Observed Size | ~ 110 kDa |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity purified. |
| Buffer | PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol. |
| Preservative | 0.02% Sodium azide |
| Stabilizer | 50% Glycerol |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | PLD2 |
| Gene Full Name | phospholipase D2 |
| Background | The protein encoded by this gene catalyzes the hydrolysis of phosphatidylcholine to phosphatidic acid and choline. The activity of the encoded enzyme is enhanced by phosphatidylinositol 4,5-bisphosphate and ADP-ribosylation factor-1. This protein localizes to the peripheral membrane and may be involved in cytoskeletal organization, cell cycle control, transcriptional regulation, and/or regulated secretion. Two transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Jul 2011] |
| Function | May have a role in signal-induced cytoskeletal regulation and/or endocytosis. [UniProt] |
| Cellular Localization | Membrane, Peripheral membrane protein. [UniProt] |
| Calculated MW | 106 kDa |
| PTM | Phosphorylated by FGR. [UniProt] |
