ARG20543
anti-Phosphoserine antibody
anti-Phosphoserine antibody for ELISA,ICC/IF,IHC-Formalin-fixed paraffin-embedded sections,Immunoprecipitation,Western blot and Other
Metabolism antibody; Neuroscience antibody; Signaling Transduction antibody
Publication1
Overview
| Product Description | Rabbit Polyclonal antibody recognizes Phosphoserine |
|---|---|
| Tested Reactivity | Other |
| Tested Application | ELISA, ICC/IF, IHC-P, IP, WB |
| Specificity | Recognizes proteins phosphorylated on serine residues. Does not cross-react with phosphotyrosine. |
| Host | Rabbit |
| Clonality | Polyclonal |
| Target Name | Phosphoserine |
| Immunogen | KLH-conjugated Phosphoserine, and phosvitin mixture |
| Conjugation | Un-conjugated |
Application Instructions
| Application Suggestion |
|
||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Rabbit immunoglobulin |
| Buffer | PBS, 50% Glycerol and 0.09% Sodium azide |
| Preservative | 0.09% Sodium azide |
| Stabilizer | 50% Glycerol |
| Concentration | 250 µg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Background | Protein phosphorylation is an important posttranslational modification that serves many key functions to regulate a protein’s activity, localization, and protein-protein interactions. Phosphorylation is catalyzed by various specific protein kinases, which involves removing a phosphate group from ATP and covalently attaching it to to a recipient protein that acts as a substrate. Most kinases act on both serine and threonine; others act on tyrosine, and a number (dual specificity kinases) act on all three. Because phosphorylation can occur at multiple sites on any given protein, it can therefore change the function or localization of that protein at any time. Changing the function of these proteins has been linked to a number of diseases, including cancer, diabetes, heart disease, inflammation and neurological disorders. |
|---|---|
| Research Area | Metabolism antibody; Neuroscience antibody; Signaling Transduction antibody |
Specific References
Switch of phosphorylation to O-GlcNAcylation of AhR contributes to vascular oxidative stress induced by benzo[a]pyrene
WB/IP / Mouse
