ARG40836
anti-Plakophilin 2 antibody
anti-Plakophilin 2 antibody for Western blot and Human,Rat
Overview
| Product Description | Rabbit Polyclonal antibody recognizes Plakophilin 2 |
|---|---|
| Tested Reactivity | Hu, Rat |
| Predict Reactivity | Ms, Hm |
| Tested Application | WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | Plakophilin 2 |
| Antigen Species | Human |
| Immunogen | Synthetic peptide corresponding to aa. 863-881 of Human Plakophilin 2. (KKTDFVNSRTAKAYHSLKD) |
| Conjugation | Un-conjugated |
| Alternate Names | ARVD9; Plakophilin-2 |
Application Instructions
| Application Suggestion |
|
||||
|---|---|---|---|---|---|
| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity purification with immunogen. |
| Buffer | 0.2% Na2HPO4, 0.9% NaCl, 0.05% Thimerosal, 0.05% Sodium azide and 5% BSA. |
| Preservative | 0.05% Thimerosal and 0.05% Sodium azide |
| Stabilizer | 5% BSA |
| Concentration | 0.5 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | PKP2 |
| Gene Full Name | plakophilin 2 |
| Background | This gene encodes a member of the arm-repeat (armadillo) and plakophilin gene families. Plakophilin proteins contain numerous armadillo repeats, localize to cell desmosomes and nuclei, and participate in linking cadherins to intermediate filaments in the cytoskeleton. This gene product may regulate the signaling activity of beta-catenin. Two alternately spliced transcripts encoding two protein isoforms have been identified. A processed pseudogene with high similarity to this locus has been mapped to chromosome 12p13. [provided by RefSeq, Jul 2008] |
| Function | May play a role in junctional plaques. [UniProt] |
| Cellular Localization | Nucleus. Cell junction, desmosome. Note=Nuclear and associated with desmosomes. [UniProt] |
| Calculated MW | 97 kDa |
