ARG56489
anti-Prostaglandin D Synthase antibody
anti-Prostaglandin D Synthase antibody for Western blot and Human,Mouse,Rat,Baboon
Overview
| Product Description | Rabbit Polyclonal antibody recognizes Prostaglandin D Synthase |
|---|---|
| Tested Reactivity | Hu, Ms, Rat, Bb |
| Tested Application | WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | Prostaglandin D Synthase |
| Antigen Species | Human |
| Immunogen | Synthetic peptide around the N-terminus of Human Prostaglandin D Synthase. |
| Conjugation | Un-conjugated |
| Alternate Names | Glutathione-requiring prostaglandin D synthase; Glutathione S-transferase; EC 2.5.1.18; GSTS; Hematopoietic prostaglandin D synthase; GSTS1-1; EC 5.3.99.2; Prostaglandin-H2 D-isomerase; PGDS; PGD2; GSTS1; Glutathione-dependent PGD synthase; H-PGDS; GST class-sigma |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity purification with immunogen. |
| Buffer | TBS (pH 7.4) |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | HPGDS |
| Gene Full Name | hematopoietic prostaglandin D synthase |
| Background | Prostaglandin-D synthase is a sigma class glutathione-S-transferase family member. The enzyme catalyzes the conversion of PGH2 to PGD2 and plays a role in the production of prostanoids in the immune system and mast cells. The presence of this enzyme can be used to identify the differentiation stage of human megakaryocytes. [provided by RefSeq, Jul 2008] |
| Function | Bifunctional enzyme which catalyzes both the conversion of PGH2 to PGD2, a prostaglandin involved in smooth muscle contraction/relaxation and a potent inhibitor of platelet aggregation, and the conjugation of glutathione with a wide range of aryl halides and organic isothiocyanates. Also exhibits low glutathione-peroxidase activity towards cumene hydroperoxide. [UniProt] |
| Calculated MW | 23 kDa |
