ARG55478
anti-Prostaglandin E Receptor EP1 antibody
anti-Prostaglandin E Receptor EP1 antibody for Western blot and Mouse
Signaling Transduction antibody
Overview
| Product Description | Rabbit Polyclonal antibody recognizes Prostaglandin E Receptor EP1 |
|---|---|
| Tested Reactivity | Ms |
| Tested Application | WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | Prostaglandin E Receptor EP1 |
| Antigen Species | Human |
| Immunogen | Synthetic peptide of Human PTGER1 (NP_000946.2) |
| Conjugation | Un-conjugated |
| Alternate Names | PGE2 receptor EP1 subtype; Prostanoid EP1 receptor; PGE receptor EP1 subtype; Prostaglandin E2 receptor EP1 subtype; EP1 |
Application Instructions
| Predict Reactivity Note | Mouse, Rat | ||||
|---|---|---|---|---|---|
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||
| Positive Control | Romas | ||||
| Observed Size | 42 kDa |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity purification with immunogen. |
| Buffer | PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol |
| Preservative | 0.02% Sodium azide |
| Stabilizer | 50% Glycerol |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links |
Swiss-port # P35375 Mouse Prostaglandin E2 receptor EP1 subtype |
|---|---|
| Gene Symbol | PTGER1 |
| Gene Full Name | prostaglandin E receptor 1 (subtype EP1), 42kDa |
| Background | The protein encoded by this gene is a member of the G protein-coupled receptor family. This protein is one of four receptors identified for prostaglandin E2 (PGE2). Through a phosphatidylinositol-calcium second messenger system, G-Q proteins mediate this receptor's activity. Knockout studies in mice suggested a role of this receptor in mediating algesia and in regulation of blood pressure. Studies in mice also suggested that this gene may mediate adrenocorticotropic hormone response to bacterial endotoxin. [provided by RefSeq, Jul 2008] |
| Function | Receptor for prostaglandin E2 (PGE2). The activity of this receptor is mediated by G(q) proteins which activate a phosphatidylinositol-calcium second messenger system. May play a role as an important modulator of renal function. Implicated the smooth muscle contractile response to PGE2 in various tissues. [UniProt] |
| Research Area | Signaling Transduction antibody |
| Calculated MW | 42 kDa |
| PTM | Phosphorylated. |
