ARG56466

anti-Prostaglandin E Synthase (cytosolic, FL) antibody

anti-Prostaglandin E Synthase (cytosolic, FL) antibody for Western blot,ICC/IF and Human,Mouse

Overview

Product Description Rabbit Polyclonal antibody recognizes Prostaglandin E Synthase (cytosolic, FL)
Tested Reactivity Hu, Ms
Tested Application ICC/IF, WB
Specificity This antibody does not react to Microsomal PGES-1 and Microsomal PGES-2.
Host Rabbit
Clonality Polyclonal
Isotype IgG
Target Name Prostaglandin E Synthase (cytosolic, FL)
Antigen Species Human
Immunogen Full length, Human recombinant Prostaglandin E Synthase (cytosolic, FL).
Conjugation Un-conjugated
Alternate Names EC 5.3.99.3; Progesterone receptor complex p23; TEBP; Hsp90 co-chaperone; P23; cPGES; Cytosolic prostaglandin E2 synthase; Prostaglandin E synthase 3; Telomerase-binding protein p23

Application Instructions

Application Suggestion
Tested Application Dilution
ICC/IF1:20 (10 µg/ml)
WB1:200 (1 µg/ml)
Application Note * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.

Properties

Form Liquid
Purification Affinity purification with immunogen.
Storage Instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database Links

GeneID: 10728 Human PTGES3

GeneID: 56351 Mouse PTGES3

Swiss-port # Q15185 Human Prostaglandin E synthase 3

Swiss-port # Q9R0Q7 Mouse Prostaglandin E synthase 3

Gene Symbol PTGES3
Gene Full Name prostaglandin E synthase 3 (cytosolic)
Function Cytosolic prostaglandin synthase that catalyzes the oxidoreduction of prostaglandin endoperoxide H2 (PGH2) to prostaglandin E2 (PGE2). Molecular chaperone that localizes to genomic response elements in a hormone-dependent manner and disrupts receptor-mediated transcriptional activation, by promoting disassembly of transcriptional regulatory complexes. Facilitates HIF alpha proteins hydroxylation via interaction with EGLN1/PHD2, leading to recruit EGLN1/PHD2 to the HSP90 pathway. [UniProt]
Calculated MW 19 kDa