ARG56494

anti-Prostaglandin E Synthase (microsomal) antibody

anti-Prostaglandin E Synthase (microsomal) antibody for Immunohistochemistry,Western blot and Human,Mouse,Rat,Sheep

Overview

Product Description Rabbit Polyclonal antibody recognizes Prostaglandin E Synthase (microsomal)
Tested Reactivity Hu, Ms, Rat, Sheep
Tested Application IHC, WB
Specificity This antibody does not react to cPGES.
Host Rabbit
Clonality Polyclonal
Isotype IgG
Target Name Prostaglandin E Synthase (microsomal)
Antigen Species Human
Immunogen Synthetic peptide around an internal region of Human Prostaglandin E Synthase (microsomal).
Conjugation Un-conjugated
Alternate Names Microsomal glutathione S-transferase 1-like 1; EC 5.3.99.3; p53-induced gene 12 protein; PIG12; MGST1L1; TP53I12; MGST-IV; Microsomal prostaglandin E synthase 1; Prostaglandin E synthase; PGES; MPGES-1; MGST1-L1; mPGES-1; PP1294; PP102; MPGES

Application Instructions

Application Suggestion
Tested Application Dilution
IHC1:125 - 1:250
WB1:200
Application Note * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.

Properties

Form Liquid
Purification Affinity purification with immunogen.
Buffer TBS (pH 7.4), 0.02% Sodium azide, 50% Glycerol and 0.1% BSA.
Preservative 0.02% Sodium azide
Stabilizer 50% Glycerol and 0.1% BSA
Storage Instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database Links

GeneID: 64292 Mouse PTGES

GeneID: 9536 Human PTGES

Swiss-port # O14684 Human Prostaglandin E synthase

Swiss-port # Q9JM51 Mouse Prostaglandin E synthase

Gene Symbol PTGES
Gene Full Name prostaglandin E synthase
Background The protein encoded by this gene is a glutathione-dependent prostaglandin E synthase. The expression of this gene has been shown to be induced by proinflammatory cytokine interleukin 1 beta (IL1B). Its expression can also be induced by tumor suppressor protein TP53, and may be involved in TP53 induced apoptosis. Knockout studies in mice suggest that this gene may contribute to the pathogenesis of collagen-induced arthritis and mediate acute pain during inflammatory responses. [provided by RefSeq, Jul 2008]
Function Catalyzes the oxidoreduction of prostaglandin endoperoxide H2 (PGH2) to prostaglandin E2 (PGE2). [UniProt]
Highlight Related products:
Prostaglandin E Synthase antibodies; Anti-Rabbit IgG secondary antibodies;
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Calculated MW 17 kDa