ARG57068
anti-QPRT antibody [24C4]
anti-QPRT antibody [24C4] for Western blot and Human
Overview
| Product Description | Mouse Monoclonal antibody [24C4] recognizes QPRT |
|---|---|
| Tested Reactivity | Hu |
| Tested Application | WB |
| Host | Mouse |
| Clonality | Monoclonal |
| Clone | 24C4 |
| Isotype | IgG2a, kappa |
| Target Name | QPRT |
| Antigen Species | Human |
| Immunogen | Recombinant fragment around aa. 1-297 of Human QPRT. |
| Conjugation | Un-conjugated |
| Alternate Names | QAPRTase; QPRTase; Quinolinate phosphoribosyltransferase [decarboxylating]; HEL-S-90n; Nicotinate-nucleotide pyrophosphorylase [carboxylating]; EC 2.4.2.19 |
Application Instructions
| Application Suggestion |
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|---|---|---|---|---|---|
| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Purification with Protein A. |
| Buffer | PBS (pH 7.4), 0.02% Sodium azide and 10% Glycerol. |
| Preservative | 0.02% Sodium azide |
| Stabilizer | 10% Glycerol |
| Concentration | 1 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links |
Swiss-port # Q15274 Human Nicotinate-nucleotide pyrophosphorylase [carboxylating] |
|---|---|
| Gene Symbol | QPRT |
| Gene Full Name | quinolinate phosphoribosyltransferase |
| Background | This gene encodes a key enzyme in catabolism of quinolinate, an intermediate in the tryptophan-nicotinamide adenine dinucleotide pathway. Quinolinate acts as a most potent endogenous exitotoxin to neurons. Elevation of quinolinate levels in the brain has been linked to the pathogenesis of neurodegenerative disorders such as epilepsy, Alzheimer's disease, and Huntington's disease. [provided by RefSeq, Jul 2008] |
| Function | Involved in the catabolism of quinolinic acid (QA). [UniProt] |
| Calculated MW | 31 kDa |
