ARG64986
anti-RAPSN / Rapsyn antibody
anti-RAPSN / Rapsyn antibody for Western blot and Human
Neuroscience antibody
Overview
| Product Description | Goat Polyclonal antibody recognizes RAPSN / Rapsyn |
|---|---|
| Tested Reactivity | Hu |
| Predict Reactivity | Ms, Rat |
| Tested Application | WB |
| Specificity | This antibody is expected to recognize both reported isoforms (NP_005046.2; NP_116034.2). |
| Host | Goat |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | RAPSN / Rapsyn |
| Antigen Species | Human |
| Immunogen | YQSNQTEKALQVWTK-C |
| Conjugation | Un-conjugated |
| Alternate Names | FADS; RING finger protein 205; 43 kDa receptor-associated protein of the synapse; Acetylcholine receptor-associated 43 kDa protein; CMS11; 43 kDa postsynaptic protein; RNF205; CMS4C; RAPsyn; RAPSYN |
Application Instructions
| Application Suggestion |
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|---|---|---|---|---|---|
| Application Note | WB: Recommend incubate at RT for 1h. * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Buffer | Tris saline (pH 7.3), 0.02% Sodium azide and 0.5% BSA |
| Preservative | 0.02% Sodium azide |
| Stabilizer | 0.5% BSA |
| Concentration | 0.5 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links |
Swiss-port # Q13702 Human 43 kDa receptor-associated protein of the synapse |
|---|---|
| Background | This gene encodes a member of a family of proteins that are receptor associated proteins of the synapse. The encoded protein contains a conserved cAMP-dependent protein kinase phosphorylation site, and plays a critical role in clustering and anchoring nicotinic acetylcholine receptors at synaptic sites by linking the receptors to the underlying postsynaptic cytoskeleton, possibly by direct association with actin or spectrin. Mutations in this gene may play a role in postsynaptic congenital myasthenic syndromes. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Apr 2011] |
| Research Area | Neuroscience antibody |
| Calculated MW | 46 kDa |
| PTM | Ubiquitinated by the BCR(KLHL8) complex, leading to its degradation. |
