ARG42860
anti-RASSF2 antibody
anti-RASSF2 antibody for Western blot and Human
Overview
| Product Description | Rabbit Polyclonal antibody recognizes RASSF2 |
|---|---|
| Tested Reactivity | Hu |
| Tested Application | WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | RASSF2 |
| Antigen Species | Human |
| Immunogen | Synthetic peptide of Human RASSF2. |
| Conjugation | Un-conjugated |
| Alternate Names | CENP-34; Ras association domain-containing protein 2; RASFADIN |
Application Instructions
| Application Suggestion |
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|---|---|---|---|---|---|
| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||
| Positive Control | HeLa | ||||
| Observed Size | ~ 39 kDa |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity purified. |
| Buffer | 50 mM Tris-Glycine (pH 7.4), 150 mM NaCl, 0.01% Sodium azide, 40% Glycerol and 0.05% BSA. |
| Preservative | 0.01% Sodium azide |
| Stabilizer | 40% Glycerol and 0.05% BSA |
| Concentration | Batch dependent |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links |
Swiss-port # P50749 Human Ras association domain-containing protein 2 |
|---|---|
| Gene Symbol | RASSF2 |
| Gene Full Name | Ras association (RalGDS/AF-6) domain family member 2 |
| Background | This gene encodes a protein that contains a Ras association domain. Similar to its cattle and sheep counterparts, this gene is located near the prion gene. Two alternatively spliced transcripts encoding the same isoform have been reported. [provided by RefSeq, Jul 2008] |
| Function | Potential tumor suppressor. Acts as a KRAS-specific effector protein. May promote apoptosis and cell cycle arrest. Stabilizes STK3/MST2 by protecting it from proteasomal degradation. [UniProt] |
| Cellular Localization | Nucleus. Cytoplasm. Chromosome, centromere, kinetochore. Note=Translocates to the cytoplasm in the presence of STK3/MST2 AND STK4/MST1. [UniProt] |
| Calculated MW | 38 kDa |
| PTM | Phosphorylated by STK3/MST2 and STK4/MST1. [UniProt] |
Images (1) Click the Picture to Zoom In
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ARG42860 anti-RASSF2 antibody WB image
Western blot: HeLa cell lysate stained with ARG42860 anti-RASSF2 antibody at 1:1000 dilution.
