ARG64433
anti-RASSF7 / HRAS1 antibody
anti-RASSF7 / HRAS1 antibody for Western blot and Human
Cell Biology and Cellular Response antibody; Controls and Markers antibody; Gene Regulation antibody
Overview
| Product Description | Goat Polyclonal antibody recognizes RASSF7 / HRAS1 |
|---|---|
| Tested Reactivity | Hu |
| Tested Application | WB |
| Host | Goat |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | RASSF7 / HRAS1 |
| Antigen Species | Human |
| Immunogen | CTDLRGLELRVQRN |
| Conjugation | Un-conjugated |
| Alternate Names | HRAS1-related cluster protein 1; HRC1; C11orf13; HRAS1; Ras association domain-containing protein 7 |
Application Instructions
| Application Suggestion |
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|---|---|---|---|---|---|
| Application Note | WB: Recommend incubate at RT for 1h. * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Purified from goat serum by antigen affinity chromatography. |
| Buffer | Tris saline (pH 7.3), 0.02% Sodium azide and 0.5% BSA. |
| Preservative | 0.02% Sodium azide |
| Stabilizer | 0.5% BSA |
| Concentration | 0.5 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links |
Swiss-port # Q02833 Human Ras association domain-containing protein 7 |
|---|---|
| Gene Symbol | RASSF7 |
| Gene Full Name | Ras association (RalGDS/AF-6) domain family (N-terminal) member 7 |
| Function | Negatively regulates stress-induced JNK activation and apoptosis by promoting MAP2K7 phosphorylation and inhibiting its ability to activate JNK. Following prolonged stress, anti-apoptotic effect stops because of degradation of RASSF7 protein via the ubiquitin-proteasome pathway. Required for the activation of AURKB and chromosomal congression during mitosis where it stimulates microtubule polymerization. [UniProt] |
| Research Area | Cell Biology and Cellular Response antibody; Controls and Markers antibody; Gene Regulation antibody |
| Calculated MW | 40 kDa |
| PTM | Polyubiquitinated and degraded by the proteasome upon prolonged stress stimuli. |
