ARG11142
anti-RBFOX2 / RBM9 antibody
anti-RBFOX2 / RBM9 antibody for IHC-Frozen sections and Human,Mouse,Rat
Overview
| Product Description | Chicken Polyclonal antibody recognizes RBFOX2 / RBM9 |
|---|---|
| Tested Reactivity | Hu, Ms, Rat |
| Tested Application | IHC-Fr |
| Host | Chicken |
| Clonality | Polyclonal |
| Isotype | IgY |
| Target Name | RBFOX2 / RBM9 |
| Antigen Species | Human |
| Immunogen | The N-terminal 99 amino acids of Human RBFOX2 / RBM9. |
| Conjugation | Un-conjugated |
| Alternate Names | RNA binding protein fox-1 homolog 2; dJ106I20.3; RTA; HRNBP2; HNRBP2; Fox-1 homolog B; RBM9; Hexaribonucleotide-binding protein 2; RNA-binding protein 9; fxh; Repressor of tamoxifen transcriptional activity; Fox-2; FOX2; RNA-binding motif protein 9 |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Buffer | PBS and 5 mM Sodium azide. |
| Preservative | 5 mM Sodium azide |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | RBFOX2 |
| Gene Full Name | RNA binding protein, fox-1 homolog (C. elegans) 2 |
| Background | This gene is one of several human genes similar to the C. elegans gene Fox-1. This gene encodes an RNA binding protein that is thought to be a key regulator of alternative exon splicing in the nervous system and other cell types. The protein binds to a conserved UGCAUG element found downstream of many alternatively spliced exons and promotes inclusion of the alternative exon in mature transcripts. The protein also interacts with the estrogen receptor 1 transcription factor and regulates estrogen receptor 1 transcriptional activity. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] |
| Function | RNA-binding protein that regulates alternative splicing events by binding to 5'-UGCAUGU-3' elements. Prevents binding of U2AF2 to the 3'-splice site. Regulates alternative splicing of tissue-specific exons and of differentially spliced exons during erythropoiesis (By similarity). RNA-binding protein that seems to act as a coregulatory factor of ER-alpha. [UniProt] |
| Cellular Localization | Nucleus. Cytoplasm. [UniProt] |
| Calculated MW | 41 kDa |
