ARG63345

anti-REV1L antibody

anti-REV1L antibody for IHC-Formalin-fixed paraffin-embedded sections and Human

Gene Regulation antibody

Overview

Product Description Goat Polyclonal antibody recognizes REV1L
Tested Reactivity Hu
Predict Reactivity Ms, Rat, Cow, Dog
Tested Application IHC-P
Specificity This antibody is expected to recognise both reported isoforms.
Host Goat
Clonality Polyclonal
Isotype IgG
Target Name REV1L
Antigen Species Human
Immunogen C-VLQQTYGSTLKVT
Conjugation Un-conjugated
Alternate Names EC 2.7.7.-; AIBP80; Rev1-like terminal deoxycytidyl transferase; Alpha integrin-binding protein 80; DNA repair protein REV1; REV1L

Application Instructions

Application Suggestion
Tested Application Dilution
IHC-P4 - 6 µg/ml
Application Note IHC-P: Antigen Retrieval: Steam tissue section in Tris/EDTA buffer (pH 9.0).
* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.

Properties

Form Liquid
Purification Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Buffer Tris saline (pH 7.3), 0.02% Sodium azide and 0.5% BSA
Preservative 0.02% Sodium azide
Stabilizer 0.5% BSA
Concentration 0.5 mg/ml
Storage Instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database Links

GeneID: 51455 Human REV1

Swiss-port # Q9UBZ9 Human DNA repair protein REV1

Background This gene encodes a protein with similarity to the S. cerevisiae mutagenesis protein Rev1. The Rev1 proteins contain a BRCT domain, which is important in protein-protein interactions. A suggested role for the human Rev1-like protein is as a scaffold that recruits DNA polymerases involved in translesion synthesis (TLS) of damaged DNA. Two alternatively spliced transcript variants that encode different proteins have been found. [provided by RefSeq, Jul 2008]
Research Area Gene Regulation antibody
Calculated MW 138 kDa