ARG41305

anti-RGS16 antibody

anti-RGS16 antibody for Western blot and Human

Overview

Product Description Rabbit Polyclonal antibody recognizes RGS16
Tested Reactivity Hu
Predict Reactivity Hu, Ms, Rat, Cow, Dog, Hrs, Pig
Tested Application WB
Host Rabbit
Clonality Polyclonal
Isotype IgG
Target Name RGS16
Antigen Species Human
Immunogen Synthetic peptide around the C-terminal region of Human RGS16. (within the following region: DAAQGKTRTLMEKDSYPRFLKSPAYRDLAAQASAASATLSSCSLDEPSHT)
Conjugation Un-conjugated
Alternate Names RGS16; RGS-r; Retinally abundant regulator of G-protein signaling; Retinal-specific RGS; A28-RGS14P; RGS-R; A28-RGS14; Regulator of G-protein signaling 16; hRGS-r

Application Instructions

Predict Reactivity Note Predicted Homology Based On Immunogen Sequence: Cow: 92%; Dog: 100%; Horse: 92%; Human: 100%; Mouse: 100%; Pig: 100%; Rat: 100%
Application Suggestion
Tested Application Dilution
WB1 µg/ml
Application Note * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
Positive Control Jurkat
Observed Size 28 kDa

Properties

Form Liquid
Purification Purification with Protein A.
Buffer PBS, 0.09% (w/v) Sodium azide and 2% Sucrose.
Preservative 0.09% (w/v) Sodium azide
Stabilizer 2% Sucrose
Concentration Batch dependent: 0.5 - 1 mg/ml
Storage Instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database Links

GeneID: 6004 Human RGS16

Swiss-port # O15492 Human Regulator of G-protein signaling 16

Gene Symbol RGS16
Gene Full Name regulator of G-protein signaling 16
Background The protein encoded by this gene belongs to the 'regulator of G protein signaling' family. It inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits. It also may play a role in regulating the kinetics of signaling in the phototransduction cascade. [provided by RefSeq, Jul 2008]
Function Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form. Binds to G(i)-alpha and G(o)-alpha, but not to G(s)-alpha. May play a role in regulating the kinetics of signaling in the phototransduction cascade. [UniProt]
Cellular Localization Membrane; Lipid-anchor. [UniProt]
Calculated MW 23 kDa
PTM Palmitoylated on Cys-2 and/or Cys-12.

Phosphorylated. Phosphorylation at Tyr-168 by EGFR enhances GTPase accelerating (GAP) activity toward GNAI1. [UniProt]