ARG59084
anti-RNASE1 / Ribonuclease A antibody
anti-RNASE1 / Ribonuclease A antibody for Western blot and Mouse
Overview
| Product Description | Rabbit Polyclonal antibody recognizes RNASE1 / Ribonuclease A |
|---|---|
| Tested Reactivity | Ms |
| Predict Reactivity | Hu |
| Tested Application | WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | RNASE1 / Ribonuclease A |
| Antigen Species | Human |
| Immunogen | Recombinant fusion protein corresponding to aa. 29-156 of Human RNASE1 / Ribonuclease A (NP_937875.1). |
| Conjugation | Un-conjugated |
| Alternate Names | Ribonuclease A; RNase A; RNS1; RAC1; RIB1; EC 3.1.27.5; Ribonuclease 1; RNase 1; Ribonuclease pancreatic; RNase UpI-1; RIB-1; HP-RNase |
Application Instructions
| Application Suggestion |
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|---|---|---|---|---|---|
| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||
| Positive Control | Mouse pancreas | ||||
| Observed Size | 15kDa |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity purified. |
| Buffer | PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol. |
| Preservative | 0.02% Sodium azide |
| Stabilizer | 50% Glycerol |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Gene Symbol | RNASE1 |
|---|---|
| Gene Full Name | ribonuclease, RNase A family, 1 (pancreatic) |
| Background | This gene encodes a member of the pancreatic-type of secretory ribonucleases, a subset of the ribonuclease A superfamily. The encoded endonuclease cleaves internal phosphodiester RNA bonds on the 3'-side of pyrimidine bases. It prefers poly(C) as a substrate and hydrolyzes 2',3'-cyclic nucleotides, with a pH optimum near 8.0. The encoded protein is monomeric and more commonly acts to degrade ds-RNA over ss-RNA. Alternative splicing occurs at this locus and four transcript variants encoding the same protein have been identified. [provided by RefSeq, Jul 2008] |
| Function | Endonuclease that catalyzes the cleavage of RNA on the 3' side of pyrimidine nucleotides. Acts on single-stranded and double-stranded RNA. [UniProt] |
| Cellular Localization | Secreted. [UniProt] |
| Calculated MW | 18 kDa |
| PTM | N-linked glycans are of complex type. [UniProt] |
