ARG63505

anti-RNF2 / RING1B / BAP1 antibody

anti-RNF2 / RING1B / BAP1 antibody for Western blot and Human

Gene Regulation antibody; Polycomb Complexes antibody

Overview

Product Description Goat Polyclonal antibody recognizes RNF2 / RING1B / BAP1
Tested Reactivity Hu
Predict Reactivity Ms, Cow, Dog
Tested Application WB
Host Goat
Clonality Polyclonal
Isotype IgG
Target Name RNF2 / RING1B / BAP1
Antigen Species Human
Immunogen C-PMELYYAPTKEHK
Conjugation Un-conjugated
Alternate Names DING; RING1b; RING1B; EC 6.3.2.-; RING finger protein 1B; RING finger protein 2; RING2; RING finger protein BAP-1; BAP-1; HIPI3; BAP1; Protein DinG; E3 ubiquitin-protein ligase RING2; Huntingtin-interacting protein 2-interacting protein 3; HIP2-interacting protein 3

Application Instructions

Application Suggestion
Tested Application Dilution
WB0.3 - 1 µg/ml
Application Note WB: Recommend incubate at RT for 1h.
* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.

Properties

Form Liquid
Purification Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Buffer Tris saline (pH 7.3), 0.02% Sodium azide and 0.5% BSA
Preservative 0.02% Sodium azide
Stabilizer 0.5% BSA
Concentration 0.5 mg/ml
Storage Instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database Links

GeneID: 6045 Human RNF2

Swiss-port # Q99496 Human E3 ubiquitin-protein ligase RING2

Background Polycomb group (PcG) of proteins form the multiprotein complexes that are important for the transcription repression of various genes involved in development and cell proliferation. The protein encoded by this gene is one of the PcG proteins. It has been shown to interact with, and suppress the activity of, transcription factor CP2 (TFCP2/CP2). Studies of the mouse counterpart suggested the involvement of this gene in the specification of anterior-posterior axis, as well as in cell proliferation in early development. This protein was also found to interact with huntingtin interacting protein 2 (HIP2), an ubiquitin-conjugating enzyme, and possess ubiquitin ligase activity. [provided by RefSeq, Jul 2008]
Highlight Related Antibody Duos and Panels:
ARG30309 Polycomb Complexes Antibody Panel (H3K27me3, EZH2, Ring1A, RNF2)
Related products:
RNF2 antibodies; RNF2 Duos / Panels; Anti-Goat IgG secondary antibodies;
Research Area Gene Regulation antibody; Polycomb Complexes antibody
Calculated MW 38 kDa
PTM Polyubiquitinated in the presence of UBE2D3 (in vitro).
Monoubiquitinated, by auto-ubiquitination.