ARG57565

anti-RPGRIP1 antibody

anti-RPGRIP1 antibody for Flow cytometry,IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human

Overview

Product Description

Rabbit Polyclonal antibody recognizes RPGRIP1

Tested Reactivity Hu
Tested Application FACS, IHC-P, WB
Host Rabbit
Clonality Polyclonal
Isotype IgG
Target Name RPGRIP1
Antigen Species Human
Immunogen KLH-conjugated synthetic peptide corresponding to aa. 530-557 (Center) of Human RPGRIP1.
Conjugation Un-conjugated
Alternate Names CORD13; X-linked retinitis pigmentosa GTPase regulator-interacting protein 1; RPGR-interacting protein 1; RGRIP; LCA6; RPGRIP1d; RGI1; RPGRIP

Application Instructions

Application Suggestion
Tested Application Dilution
FACS1:10 - 1:50
IHC-P1:50 - 1:100
WB1:1000
Application Note * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
Positive Control HL-60

Properties

Form Liquid
Purification Purification with Protein A and immunogen peptide.
Buffer PBS and 0.09% (W/V) Sodium azide.
Preservative 0.09% (W/V) Sodium azide.
Storage Instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database Links

GeneID: 57096 Human RPGRIP1

Swiss-port # Q96KN7 Human X-linked retinitis pigmentosa GTPase regulator-interacting protein 1

Gene Symbol RPGRIP1
Gene Full Name retinitis pigmentosa GTPase regulator interacting protein 1
Background This gene encodes a photoreceptor protein that interacts with retinitis pigmentosa GTPase regulator protein and is a key component of cone and rod photoreceptor cells. Mutations in this gene lead to autosomal recessive congenital blindness. [provided by RefSeq, Oct 2008]
Function May function as scaffolding protein. Required for normal location of RPGR at the connecting cilium of photoreceptor cells. Required for normal disk morphogenesis and disk organization in the outer segment of photoreceptor cells and for survival of photoreceptor cells. [UniProt]
Cellular Localization Cell projection, cilium. Note=Situated between the axonemal microtubules and the plasma membrane {ECO:0000250|UniProtKB:Q9EPQ2}
Calculated MW 147 kDa