ARG42888
anti-RPS6KA6 / RSK4 antibody
anti-RPS6KA6 / RSK4 antibody for Western blot,IHC-Formalin-fixed paraffin-embedded sections,ICC/IF,Flow cytometry and Human
Overview
| Product Description | Rabbit Polyclonal antibody recognizes RPS6KA6 / RSK4 |
|---|---|
| Tested Reactivity | Hu |
| Tested Application | FACS, ICC/IF, IHC-P, WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | RPS6KA6 / RSK4 |
| Antigen Species | Human |
| Immunogen | Synthetic peptide derived from Human RPS6KA6 / RSK4. |
| Conjugation | Un-conjugated |
| Alternate Names | Ribosomal S6 kinase 4; pp90RSK4; p90-RSK 6; p90RSK6; RSK-4; PP90RSK4; S6K-alpha-6; EC 2.7.11.1; 90 kDa ribosomal protein S6 kinase 6; RSK4; Ribosomal protein S6 kinase alpha-6 |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||||||
| Positive Control | SH-SY5Y | ||||||||||
| Observed Size | ~ 88 kDa |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity purified. |
| Buffer | PBS (pH 7.4), 150 mM NaCl, 0.02% Sodium azide and 50% Glycerol. |
| Preservative | 0.02% Sodium azide |
| Stabilizer | 50% Glycerol |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links |
Swiss-port # Q9UK32 Human Ribosomal protein S6 kinase alpha-6 |
|---|---|
| Gene Symbol | RPS6KA6 |
| Gene Full Name | ribosomal protein S6 kinase, 90kDa, polypeptide 6 |
| Background | This gene encodes a member of ribosomal S6 kinase family, serine-threonine protein kinases which are regulated by growth factors. The encoded protein may be distinct from other members of this family, however, as studies suggest it is not growth factor dependent and may not participate in the same signaling pathways. [provided by RefSeq, Jan 2010] |
| Function | Constitutively active serine/threonine-protein kinase that exhibits growth-factor-independent kinase activity and that may participate in p53/TP53-dependent cell growth arrest signaling and play an inhibitory role during embryogenesis. [UniProt] |
| Cellular Localization | Cytoplasm, cytosol. Nucleus. Note=Predominantly cytosolic. [UniProt] |
| Calculated MW | 84 kDa |
| PTM | Phosphorylated at Ser-232, Ser-372, and Ser-389 in serum-starved cells. [UniProt] |
